重要自身免疫性疾病的发病机制及其免疫干预策略

自身免疫病是由于机体免疫系统对自身组织和器官发生了免疫应答并造成组织损伤和功能障碍的一类疾病。在“211工程”三期建设中,上海市免疫学研究所和上海市风湿病学研究所的研究团队以免疫调节与免疫病理为主题,围绕系统性红斑狼疮、类风湿性关节炎和银屑病等3大疾病的发病机制和免疫调节开展深入研究,发展免疫干预新靶点与新策略,为上述疾病的防治和诊断提供重要的新策略。系统性红斑狼疮的发病机制及临床治疗技术研究项目获国家科学技术进步奖二等奖。...

Full description

Saved in:
Bibliographic Details
Published in上海交通大学学报(医学版) Vol. 32; no. 9; pp. 1128 - 1134
Main Author 沈浩 王颖 王佳琦 李宁丽 王宏林 沈南
Format Journal Article
LanguageChinese
Published 上海交通大学 医学院上海市免疫学研究所,上海,200025%上海交通大学 医学院附属仁济医院 上海市风湿病学研究所,上海,200001 2012
Subjects
Online AccessGet full text
ISSN1674-8115
DOI10.3969/j.issn.1674-8115.2012.09.003

Cover

More Information
Summary:自身免疫病是由于机体免疫系统对自身组织和器官发生了免疫应答并造成组织损伤和功能障碍的一类疾病。在“211工程”三期建设中,上海市免疫学研究所和上海市风湿病学研究所的研究团队以免疫调节与免疫病理为主题,围绕系统性红斑狼疮、类风湿性关节炎和银屑病等3大疾病的发病机制和免疫调节开展深入研究,发展免疫干预新靶点与新策略,为上述疾病的防治和诊断提供重要的新策略。系统性红斑狼疮的发病机制及临床治疗技术研究项目获国家科学技术进步奖二等奖。
Bibliography:Autoimmune diseases arise from inappropriate immune responses against molecules and organs normally present in the body, resulting in tissue damage and functional defects. Supported by "211 Project", the research groups from Shanghai Institute of Immunology and Shanghai Institute of Rheumatology have been working cooperatively to explore the immuno-regulation and immuno-pathogenesis of important autoimmune disorders including systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and psoriasis (PS), in which facilitate the diagnosis and intervention of the diseases. One of the research achievements, the pathogenesis of SLE and its novel therapeutic strategy, was awarded the second prize of 2009 National Science and Technology Progress Award.
SHEN Hao, WANG Ying , WANG Jia-qi , LI Nlng-li , WANG Hong-lin , SHEN Nan (1. Shanghai Institute of Immunology, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China;2. Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiaotong Universit
ISSN:1674-8115
DOI:10.3969/j.issn.1674-8115.2012.09.003