Silicone breast implant modification review: overcoming capsular contracture

Background Silicone implants are biomaterials that are frequently used in the medical industry due to their physiological inertness and low toxicity. However, capsular contracture remains a concern in long-term transplantation. To date, several studies have been conducted to overcome this problem. T...

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Published inBiomaterials research Vol. 22; no. 1; pp. 37 - 9
Main Authors Shin, Byung Ho, Kim, Byung Hwi, Kim, Sujin, Lee, Kangwon, Choy, Young Bin, Heo, Chan Yeong
Format Journal Article
LanguageEnglish
Published London BioMed Central 20.12.2018
BioMed Central Ltd
American Association for the Advancement of Science (AAAS)
한국생체재료학회
Subjects
Adsorption
Analysis
Antibiotics
Antiinflammatory agents
Asthma
Biomaterials
Biomedical materials
Breast implants
Capsular contracture
Chemistry and Materials Science
Collagen
Complications and side effects
Cytokines
Fibroblasts
Fibrosis
Foreign body reaction
Growth factors
Immunosuppressive agents
Inflammation
Materials Science
Medical silicones
Modification
Physiology
Plastic surgery
Properties
Proteins
Review
Reviews
Silicone implant
Silicones
Topography
Toxicity
Transplantation
Transplants & implants
의공학
Modification
Silicone implant
Capsular contracture
Inflammation
Foreign body reaction
Fibrosis
Online AccessGet full text
ISSN2055-7124
1226-4601
2055-7124
DOI10.1186/s40824-018-0147-5

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Abstract Background Silicone implants are biomaterials that are frequently used in the medical industry due to their physiological inertness and low toxicity. However, capsular contracture remains a concern in long-term transplantation. To date, several studies have been conducted to overcome this problem. This review summarizes and explores these trends. Main body First, we examined the overall foreign body response from initial inflammation to fibrosis capsule formation in detail and introduced various studies to overcome capsular contracture. Secondly, we introduced that the main research approaches are to inhibit fibrosis with anti-inflammatory drugs or antibiotics, to control the topography of the surface of silicone implants, and to administer plasma treatment. Each study examined aspects of the various mechanisms by which capsular contracture could occur, and addressed the effects of inhibiting fibrosis. Conclusion This review introduces various silicone surface modification methods to date and examines their limitations. This review will help identify new directions in inhibiting the fibrosis of silicone implants.
AbstractList Silicone implants are biomaterials that are frequently used in the medical industry due to their physiological inertness and low toxicity. However, capsular contracture remains a concern in long-term transplantation. To date, several studies have been conducted to overcome this problem. This review summarizes and explores these trends. This review introduces various silicone surface modification methods to date and examines their limitations. This review will help identify new directions in inhibiting the fibrosis of silicone implants.
Background Silicone implants are biomaterials that are frequently used in the medical industry due to their physiological inertness and low toxicity. However, capsular contracture remains a concern in long-term transplantation. To date, several studies have been conducted to overcome this problem. This review summarizes and explores these trends. Main body First, we examined the overall foreign body response from initial inflammation to fibrosis capsule formation in detail and introduced various studies to overcome capsular contracture. Secondly, we introduced that the main research approaches are to inhibit fibrosis with anti-inflammatory drugs or antibiotics, to control the topography of the surface of silicone implants, and to administer plasma treatment. Each study examined aspects of the various mechanisms by which capsular contracture could occur, and addressed the effects of inhibiting fibrosis. Conclusion This review introduces various silicone surface modification methods to date and examines their limitations. This review will help identify new directions in inhibiting the fibrosis of silicone implants. Keywords: Fibrosis, Inflammation, Silicone implant, Foreign body reaction, Capsular contracture, Modification
Silicone implants are biomaterials that are frequently used in the medical industry due to their physiological inertness and low toxicity. However, capsular contracture remains a concern in long-term transplantation. To date, several studies have been conducted to overcome this problem. This review summarizes and explores these trends. First, we examined the overall foreign body response from initial inflammation to fibrosis capsule formation in detail and introduced various studies to overcome capsular contracture. Secondly, we introduced that the main research approaches are to inhibit fibrosis with anti-inflammatory drugs or antibiotics, to control the topography of the surface of silicone implants, and to administer plasma treatment. Each study examined aspects of the various mechanisms by which capsular contracture could occur, and addressed the effects of inhibiting fibrosis. This review introduces various silicone surface modification methods to date and examines their limitations. This review will help identify new directions in inhibiting the fibrosis of silicone implants.
Silicone implants are biomaterials that are frequently used in the medical industry due to their physiological inertness and low toxicity. However, capsular contracture remains a concern in long-term transplantation. To date, several studies have been conducted to overcome this problem. This review summarizes and explores these trends.BACKGROUNDSilicone implants are biomaterials that are frequently used in the medical industry due to their physiological inertness and low toxicity. However, capsular contracture remains a concern in long-term transplantation. To date, several studies have been conducted to overcome this problem. This review summarizes and explores these trends.First, we examined the overall foreign body response from initial inflammation to fibrosis capsule formation in detail and introduced various studies to overcome capsular contracture. Secondly, we introduced that the main research approaches are to inhibit fibrosis with anti-inflammatory drugs or antibiotics, to control the topography of the surface of silicone implants, and to administer plasma treatment. Each study examined aspects of the various mechanisms by which capsular contracture could occur, and addressed the effects of inhibiting fibrosis.MAIN BODYFirst, we examined the overall foreign body response from initial inflammation to fibrosis capsule formation in detail and introduced various studies to overcome capsular contracture. Secondly, we introduced that the main research approaches are to inhibit fibrosis with anti-inflammatory drugs or antibiotics, to control the topography of the surface of silicone implants, and to administer plasma treatment. Each study examined aspects of the various mechanisms by which capsular contracture could occur, and addressed the effects of inhibiting fibrosis.This review introduces various silicone surface modification methods to date and examines their limitations. This review will help identify new directions in inhibiting the fibrosis of silicone implants.CONCLUSIONThis review introduces various silicone surface modification methods to date and examines their limitations. This review will help identify new directions in inhibiting the fibrosis of silicone implants.
Abstract Background Silicone implants are biomaterials that are frequently used in the medical industry due to their physiological inertness and low toxicity. However, capsular contracture remains a concern in long-term transplantation. To date, several studies have been conducted to overcome this problem. This review summarizes and explores these trends. Main body First, we examined the overall foreign body response from initial inflammation to fibrosis capsule formation in detail and introduced various studies to overcome capsular contracture. Secondly, we introduced that the main research approaches are to inhibit fibrosis with anti-inflammatory drugs or antibiotics, to control the topography of the surface of silicone implants, and to administer plasma treatment. Each study examined aspects of the various mechanisms by which capsular contracture could occur, and addressed the effects of inhibiting fibrosis. Conclusion This review introduces various silicone surface modification methods to date and examines their limitations. This review will help identify new directions in inhibiting the fibrosis of silicone implants.
Background: Silicone implants are biomaterials that are frequently used in the medical industry due to their physiological inertness and low toxicity. However, capsular contracture remains a concern in long-term transplantation. To date, several studies have been conducted to overcome this problem. This review summarizes and explores these trends. Main body: First, we examined the overall foreign body response from initial inflammation to fibrosis capsule formation in detail and introduced various studies to overcome capsular contracture. Secondly, we introduced that the main research approaches are to inhibit fibrosis with anti-inflammatory drugs or antibiotics, to control the topography of the surface of silicone implants, and to administer plasma treatment. Each study examined aspects of the various mechanisms by which capsular contracture could occur, and addressed the effects of inhibiting fibrosis. Conclusion: This review introduces various silicone surface modification methods to date and examines their limitations. This review will help identify new directions in inhibiting the fibrosis of silicone implants. KCI Citation Count: 1
Background Silicone implants are biomaterials that are frequently used in the medical industry due to their physiological inertness and low toxicity. However, capsular contracture remains a concern in long-term transplantation. To date, several studies have been conducted to overcome this problem. This review summarizes and explores these trends. Main body First, we examined the overall foreign body response from initial inflammation to fibrosis capsule formation in detail and introduced various studies to overcome capsular contracture. Secondly, we introduced that the main research approaches are to inhibit fibrosis with anti-inflammatory drugs or antibiotics, to control the topography of the surface of silicone implants, and to administer plasma treatment. Each study examined aspects of the various mechanisms by which capsular contracture could occur, and addressed the effects of inhibiting fibrosis. Conclusion This review introduces various silicone surface modification methods to date and examines their limitations. This review will help identify new directions in inhibiting the fibrosis of silicone implants.
Background Silicone implants are biomaterials that are frequently used in the medical industry due to their physiological inertness and low toxicity. However, capsular contracture remains a concern in long-term transplantation. To date, several studies have been conducted to overcome this problem. This review summarizes and explores these trends. Main body First, we examined the overall foreign body response from initial inflammation to fibrosis capsule formation in detail and introduced various studies to overcome capsular contracture. Secondly, we introduced that the main research approaches are to inhibit fibrosis with anti-inflammatory drugs or antibiotics, to control the topography of the surface of silicone implants, and to administer plasma treatment. Each study examined aspects of the various mechanisms by which capsular contracture could occur, and addressed the effects of inhibiting fibrosis. Conclusion This review introduces various silicone surface modification methods to date and examines their limitations. This review will help identify new directions in inhibiting the fibrosis of silicone implants.
Audience Academic
Author Kim, Sujin
Kim, Byung Hwi
Shin, Byung Ho
Choy, Young Bin
Lee, Kangwon
Heo, Chan Yeong
Author_xml – sequence: 1
  givenname: Byung Ho
  surname: Shin
  fullname: Shin, Byung Ho
  organization: Department of Biomedical Engineering, Seoul National University College of Medicine
– sequence: 2
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  surname: Kim
  fullname: Kim, Byung Hwi
  organization: Department of Biomedical Engineering, Seoul National University College of Medicine
– sequence: 3
  givenname: Sujin
  surname: Kim
  fullname: Kim, Sujin
  organization: Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University
– sequence: 4
  givenname: Kangwon
  surname: Lee
  fullname: Lee, Kangwon
  organization: Department of Transdisciplinary Studies, Graduate School of Convergence Science and Technology, Seoul National University, Advanced Institutes of Convergence Technology
– sequence: 5
  givenname: Young Bin
  surname: Choy
  fullname: Choy, Young Bin
  organization: Department of Biomedical Engineering, Seoul National University College of Medicine, Interdisciplinary Program for Bioengineering, College of Engineering, Seoul National University, Institute of Medical & Biological Engineering, Medical Research Center, Seoul National University
– sequence: 6
  givenname: Chan Yeong
  orcidid: 0000-0001-9003-7365
  surname: Heo
  fullname: Heo, Chan Yeong
  email: lionheo@gmail.com
  organization: Interdisciplinary Program for Bioengineering, College of Engineering, Seoul National University, Department of Plastic and Reconstructive Surgery, College of Medicine, Seoul National University, Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital
BackLink https://www.ncbi.nlm.nih.gov/pubmed/30598837$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1161/01.RES.0000191547.64391.e3
10.1038/nrd.2015.2
10.1007/BF00918135
10.1016/S0094-1298(20)32393-2
10.1097/01.prs.0000435317.76381.68
10.1189/jlb.0605289
10.1038/labinvest.3700669
10.1016/0304-4165(93)90123-P
10.1016/j.biomaterials.2009.07.027
10.1100/tsw.2010.229
10.1051/epjap:2006034
10.1002/lary.24477
10.1016/j.biomaterials.2015.02.003
10.1038/nbt.2580
10.1016/j.it.2009.12.001
10.3892/etm.2010.136
10.1378/chest.123.3_suppl.417S
10.1289/ehp.98106393
10.1371/journal.pone.0092273
10.1002/bjs.9084
10.1096/fj.03-1273rev
10.1016/S0142-9612(02)00429-5
10.1001/jamasurg.2017.4026
10.1093/asj/sjx150
10.1097/01.prs.0000176894.70848.98
10.1139/y95-028
10.1016/j.ijso.2016.04.001
10.5772/21790
10.1046/j.0022-202x.2001.01690.x
10.1097/01.sap.0000252714.72161.4a
10.1007/s00266-005-5049-y
10.1007/s00268-012-1450-2
10.1080/08941930490502844
10.1016/S0094-1298(20)32397-X
10.1016/0007-1226(91)90204-W
10.1046/j.1365-2222.2002.01293.x
10.1097/01.sap.0000134508.43550.6f
10.1088/1748-6041/1/1/R01
10.1254/jjp.60.91
10.1038/ni1276
10.1097/01.prs.0000237013.50283.d2
10.1182/blood.V55.1.156.156
10.1097/PRS.0b013e3181fad34d
10.1002/jbm.a.35958
10.1089/ten.2006.12.1955
10.1097/SAP.0b013e3181c60f1f
10.1016/j.smim.2007.11.004
10.1177/1090820X13491490
10.1056/NEJMra071371
10.3390/ma8095269
10.1016/j.jconrel.2014.12.021
10.1183/09031936.00152106
10.1097/01.prs.0000176259.66948.e7
10.1089/ten.2005.11.1
10.1177/1090820X12455429
10.1016/j.actbio.2010.12.024
10.1097/PRS.0b013e3181dbc313
10.1159/000121501
10.5999/aps.2015.42.5.532
10.1017/S1462399411001943
10.1016/S1286-4579(99)00257-9
10.1006/bbrc.1996.1508
10.1016/S0306-3623(97)00307-8
10.1007/s000110050222
10.1016/j.jiec.2018.02.013
10.1146/annurev.matsci.31.1.81
10.1165/ajrcmb.16.6.9191468
10.1111/j.1365-2222.2006.02498.x
10.1002/jcp.1041380112
10.1034/j.1600-065X.2000.17706.x
10.1097/AIA.0b013e318034194e
10.1038/nri.2017.1
10.1097/PRS.0000000000001576
10.1046/j.1440-1711.2001.01020.x
10.1007/BF01844196
10.1371/journal.pone.0192108
10.1038/nri978
10.1007/s00266-013-0087-3
10.1016/j.actbio.2017.01.033
10.1097/00000637-199204000-00010
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Issue 1
Keywords Modification
Silicone implant
Capsular contracture
Inflammation
Foreign body reaction
Fibrosis
Language English
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References e_1_3_5_27_2
e_1_3_5_25_2
e_1_3_5_44_2
e_1_3_5_65_2
e_1_3_5_46_2
e_1_3_5_67_2
e_1_3_5_88_2
e_1_3_5_48_2
e_1_3_5_69_2
e_1_3_5_29_2
e_1_3_5_82_2
Mastalerz L (e_1_3_5_87_2) 2010; 120
e_1_3_5_80_2
e_1_3_5_40_2
e_1_3_5_61_2
e_1_3_5_86_2
Feghali CA (e_1_3_5_28_2) 1997; 2
e_1_3_5_42_2
e_1_3_5_84_2
Vroman L (e_1_3_5_24_2) 1980; 55
e_1_3_5_9_2
Barnea Y (e_1_3_5_63_2) 2018; 1
e_1_3_5_3_2
e_1_3_5_5_2
e_1_3_5_39_2
e_1_3_5_16_2
e_1_3_5_37_2
Hedén P (e_1_3_5_11_2) 2001; 28
e_1_3_5_14_2
e_1_3_5_12_2
e_1_3_5_35_2
e_1_3_5_10_2
e_1_3_5_33_2
e_1_3_5_54_2
e_1_3_5_77_2
Horbett T (e_1_3_5_23_2) 2004; 2
e_1_3_5_56_2
e_1_3_5_79_2
e_1_3_5_58_2
e_1_3_5_18_2
e_1_3_5_90_2
e_1_3_5_50_2
e_1_3_5_73_2
e_1_3_5_52_2
e_1_3_5_75_2
e_1_3_5_31_2
e_1_3_5_26_2
e_1_3_5_22_2
e_1_3_5_66_2
e_1_3_5_89_2
e_1_3_5_45_2
e_1_3_5_68_2
e_1_3_5_47_2
e_1_3_5_49_2
e_1_3_5_81_2
e_1_3_5_2_2
e_1_3_5_60_2
e_1_3_5_62_2
e_1_3_5_85_2
e_1_3_5_41_2
e_1_3_5_64_2
e_1_3_5_83_2
e_1_3_5_8_2
e_1_3_5_20_2
Hester T (e_1_3_5_7_2) 2001; 28
Amano Y (e_1_3_5_71_2) 1993; 43
e_1_3_5_4_2
e_1_3_5_6_2
e_1_3_5_17_2
e_1_3_5_38_2
e_1_3_5_15_2
e_1_3_5_36_2
Brett D (e_1_3_5_43_2) 2008; 20
e_1_3_5_13_2
e_1_3_5_34_2
e_1_3_5_32_2
e_1_3_5_55_2
e_1_3_5_76_2
e_1_3_5_57_2
e_1_3_5_78_2
e_1_3_5_59_2
e_1_3_5_19_2
e_1_3_5_70_2
e_1_3_5_91_2
Latour RA (e_1_3_5_21_2) 2005; 1
e_1_3_5_51_2
e_1_3_5_72_2
e_1_3_5_53_2
e_1_3_5_74_2
e_1_3_5_30_2
References_xml – ident: e_1_3_5_25_2
  doi: 10.1161/01.RES.0000191547.64391.e3
– ident: e_1_3_5_38_2
  doi: 10.1038/nrd.2015.2
– ident: e_1_3_5_81_2
  doi: 10.1007/BF00918135
– volume: 28
  start-page: 531
  issue: 3
  year: 2001
  ident: e_1_3_5_11_2
  article-title: Breast augmentation with anatomical cohesive gel implants: the world's largest current experience
  publication-title: Clin Plast Surg
  doi: 10.1016/S0094-1298(20)32393-2
– ident: e_1_3_5_48_2
  doi: 10.1097/01.prs.0000435317.76381.68
– volume: 1
  start-page: 9
  year: 2018
  ident: e_1_3_5_63_2
  article-title: Plasma activation of a breast implant shell in conjunction with antibacterial irrigants enhances antibacterial activity
  publication-title: Aesthet Surg J
– ident: e_1_3_5_34_2
  doi: 10.1189/jlb.0605289
– volume: 2
  start-page: d12
  issue: 1
  year: 1997
  ident: e_1_3_5_28_2
  article-title: Cytokines in acute and chronic inflammation
  publication-title: Front Biosci
– ident: e_1_3_5_75_2
  doi: 10.1038/labinvest.3700669
– ident: e_1_3_5_89_2
  doi: 10.1016/0304-4165(93)90123-P
– ident: e_1_3_5_6_2
– ident: e_1_3_5_19_2
  doi: 10.1016/j.biomaterials.2009.07.027
– ident: e_1_3_5_83_2
  doi: 10.1100/tsw.2010.229
– ident: e_1_3_5_67_2
  doi: 10.1051/epjap:2006034
– ident: e_1_3_5_79_2
  doi: 10.1002/lary.24477
– ident: e_1_3_5_12_2
  doi: 10.1016/j.biomaterials.2015.02.003
– ident: e_1_3_5_45_2
– ident: e_1_3_5_22_2
  doi: 10.1038/nbt.2580
– ident: e_1_3_5_14_2
  doi: 10.1016/j.it.2009.12.001
– volume: 1
  start-page: 270
  year: 2005
  ident: e_1_3_5_21_2
  article-title: Biomaterials: protein-surface interactions
  publication-title: Encyclopedia of biomaterials and biomedical engineering
– ident: e_1_3_5_65_2
  doi: 10.3892/etm.2010.136
– ident: e_1_3_5_78_2
  doi: 10.1378/chest.123.3_suppl.417S
– ident: e_1_3_5_8_2
  doi: 10.1289/ehp.98106393
– ident: e_1_3_5_37_2
  doi: 10.1371/journal.pone.0092273
– ident: e_1_3_5_59_2
  doi: 10.1002/bjs.9084
– ident: e_1_3_5_36_2
  doi: 10.1096/fj.03-1273rev
– ident: e_1_3_5_15_2
  doi: 10.1016/S0142-9612(02)00429-5
– ident: e_1_3_5_53_2
  doi: 10.1001/jamasurg.2017.4026
– ident: e_1_3_5_54_2
  doi: 10.1093/asj/sjx150
– ident: e_1_3_5_55_2
  doi: 10.1097/01.prs.0000176894.70848.98
– ident: e_1_3_5_84_2
  doi: 10.1139/y95-028
– ident: e_1_3_5_3_2
  doi: 10.1016/j.ijso.2016.04.001
– volume: 2
  start-page: 237
  year: 2004
  ident: e_1_3_5_23_2
  article-title: The role of adsorbed proteins in tissue response to biomaterials. Biomaterials science: an introduction to
  publication-title: materials in medicine
– ident: e_1_3_5_16_2
  doi: 10.5772/21790
– volume: 43
  start-page: 176
  issue: 2
  year: 1993
  ident: e_1_3_5_71_2
  article-title: Inhibition by glucocorticoids of the formation of interleukin-1 alpha, interleukin-1 beta, and interleukin-6: mediation by decreased mRNA stability
  publication-title: Mol Pharmacol
– ident: e_1_3_5_90_2
  doi: 10.1046/j.0022-202x.2001.01690.x
– ident: e_1_3_5_60_2
  doi: 10.1097/01.sap.0000252714.72161.4a
– ident: e_1_3_5_61_2
  doi: 10.1007/s00266-005-5049-y
– ident: e_1_3_5_2_2
  doi: 10.1007/s00268-012-1450-2
– ident: e_1_3_5_56_2
  doi: 10.1080/08941930490502844
– volume: 28
  start-page: 579
  issue: 3
  year: 2001
  ident: e_1_3_5_7_2
  article-title: The polyurethane-covered mammary prosthesis: facts and fiction (II)
  publication-title: Clin Plast Surg
  doi: 10.1016/S0094-1298(20)32397-X
– ident: e_1_3_5_44_2
  doi: 10.1016/0007-1226(91)90204-W
– ident: e_1_3_5_32_2
  doi: 10.1046/j.1365-2222.2002.01293.x
– ident: e_1_3_5_10_2
  doi: 10.1097/01.sap.0000134508.43550.6f
– ident: e_1_3_5_41_2
  doi: 10.1088/1748-6041/1/1/R01
– ident: e_1_3_5_76_2
  doi: 10.1254/jjp.60.91
– ident: e_1_3_5_29_2
  doi: 10.1038/ni1276
– ident: e_1_3_5_47_2
  doi: 10.1097/01.prs.0000237013.50283.d2
– volume: 55
  start-page: 156
  issue: 1
  year: 1980
  ident: e_1_3_5_24_2
  article-title: Interaction of high molecular weight kininogen, factor XII, and fibrinogen in plasma at interfaces
  publication-title: Blood
  doi: 10.1182/blood.V55.1.156.156
– ident: e_1_3_5_26_2
– ident: e_1_3_5_46_2
  doi: 10.1097/PRS.0b013e3181fad34d
– ident: e_1_3_5_18_2
  doi: 10.1002/jbm.a.35958
– ident: e_1_3_5_17_2
  doi: 10.1089/ten.2006.12.1955
– ident: e_1_3_5_58_2
  doi: 10.1097/SAP.0b013e3181c60f1f
– ident: e_1_3_5_5_2
  doi: 10.1016/j.smim.2007.11.004
– ident: e_1_3_5_64_2
  doi: 10.1177/1090820X13491490
– ident: e_1_3_5_86_2
  doi: 10.1056/NEJMra071371
– ident: e_1_3_5_39_2
  doi: 10.3390/ma8095269
– ident: e_1_3_5_51_2
  doi: 10.1016/j.jconrel.2014.12.021
– ident: e_1_3_5_35_2
  doi: 10.1183/09031936.00152106
– ident: e_1_3_5_9_2
  doi: 10.1097/01.prs.0000176259.66948.e7
– ident: e_1_3_5_27_2
  doi: 10.1089/ten.2005.11.1
– ident: e_1_3_5_62_2
  doi: 10.1177/1090820X12455429
– ident: e_1_3_5_66_2
  doi: 10.1016/j.actbio.2010.12.024
– ident: e_1_3_5_91_2
  doi: 10.1097/PRS.0b013e3181dbc313
– ident: e_1_3_5_50_2
  doi: 10.1159/000121501
– ident: e_1_3_5_4_2
  doi: 10.5999/aps.2015.42.5.532
– ident: e_1_3_5_42_2
  doi: 10.1017/S1462399411001943
– ident: e_1_3_5_80_2
  doi: 10.1016/S1286-4579(99)00257-9
– ident: e_1_3_5_74_2
  doi: 10.1006/bbrc.1996.1508
– ident: e_1_3_5_88_2
  doi: 10.1016/S0306-3623(97)00307-8
– ident: e_1_3_5_70_2
  doi: 10.1007/s000110050222
– ident: e_1_3_5_73_2
  doi: 10.1016/j.jiec.2018.02.013
– ident: e_1_3_5_20_2
  doi: 10.1146/annurev.matsci.31.1.81
– ident: e_1_3_5_77_2
  doi: 10.1165/ajrcmb.16.6.9191468
– ident: e_1_3_5_85_2
  doi: 10.1111/j.1365-2222.2006.02498.x
– volume: 20
  start-page: 347
  issue: 12
  year: 2008
  ident: e_1_3_5_43_2
  article-title: A review of collagen and collagen-based wound dressings
  publication-title: Wounds
– ident: e_1_3_5_82_2
  doi: 10.1002/jcp.1041380112
– ident: e_1_3_5_33_2
  doi: 10.1034/j.1600-065X.2000.17706.x
– ident: e_1_3_5_30_2
  doi: 10.1097/AIA.0b013e318034194e
– ident: e_1_3_5_72_2
  doi: 10.1038/nri.2017.1
– ident: e_1_3_5_68_2
  doi: 10.1097/PRS.0000000000001576
– volume: 120
  start-page: 103
  issue: 3
  year: 2010
  ident: e_1_3_5_87_2
  article-title: Antileukotriene drugs in the treatment of asthma
  publication-title: Pol Arch Med Wewn
– ident: e_1_3_5_31_2
  doi: 10.1046/j.1440-1711.2001.01020.x
– ident: e_1_3_5_69_2
  doi: 10.1007/BF01844196
– ident: e_1_3_5_13_2
  doi: 10.1371/journal.pone.0192108
– ident: e_1_3_5_40_2
  doi: 10.1038/nri978
– ident: e_1_3_5_57_2
  doi: 10.1007/s00266-013-0087-3
– ident: e_1_3_5_52_2
  doi: 10.1016/j.actbio.2017.01.033
– ident: e_1_3_5_49_2
  doi: 10.1097/00000637-199204000-00010
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Snippet Background Silicone implants are biomaterials that are frequently used in the medical industry due to their physiological inertness and low toxicity. However,...
Silicone implants are biomaterials that are frequently used in the medical industry due to their physiological inertness and low toxicity. However, capsular...
Background Silicone implants are biomaterials that are frequently used in the medical industry due to their physiological inertness and low toxicity. However,...
Abstract Background Silicone implants are biomaterials that are frequently used in the medical industry due to their physiological inertness and low toxicity....
Background: Silicone implants are biomaterials that are frequently used in the medical industry due to their physiological inertness and low toxicity. However,...
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StartPage 37
SubjectTerms Adsorption
Analysis
Antibiotics
Antiinflammatory agents
Asthma
Biomaterials
Biomedical materials
Breast implants
Capsular contracture
Chemistry and Materials Science
Collagen
Complications and side effects
Cytokines
Fibroblasts
Fibrosis
Foreign body reaction
Growth factors
Immunosuppressive agents
Inflammation
Materials Science
Medical silicones
Modification
Physiology
Plastic surgery
Properties
Proteins
Review
Reviews
Silicone implant
Silicones
Topography
Toxicity
Transplantation
Transplants & implants
의공학
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Title Silicone breast implant modification review: overcoming capsular contracture
URI https://link.springer.com/article/10.1186/s40824-018-0147-5
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