Ward区的随访研究

目的深入研究Ward区做为骨密度随访指标的临床意义。方法采用美国Norland XR-600双能X线骨密度仪,通过测定58例骨质疏松或骨量减少患者6个月内左股骨近端、正位腰椎、全身骨密度,观察股骨颈、Ward区、L2-4、全身骨密度（BMD）及骨矿含量与瘦体重的百分比（%TBMC/FFM）随时间的变化规律及临床特点;通过测定58例患者血钙、血磷、碱性磷酸酶等生化指标,分析其与骨密度的相关性。结果 1所有患者全身BMD降低,%TBMC/FFM低于5%或为正常低值。2服药治疗组6个月后Ward区BMD显著增加,P=0.0028,P〈0.05,差异有统计学意义;股骨颈、L2-4、全身BMD、%TBM...

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Published in中国骨质疏松杂志 Vol. 22; no. 11; pp. 1399 - 1403
Main Author 孙蕴 马兆坤 潘克梫 聂庆东 尉可道 王建超
Format Journal Article
LanguageChinese
Published 清华大学医院放射科,北京,100084%清华大学医院骨科,北京,100084%清华大学医院检验科,北京,100084%中国疾控中心辐射防护与核安全医学所,北京,100084 2016
Subjects
Ward区
X线
骨密度
骨密度
Bone mineral density
Ward region
X-ray
Ward区
X线
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ISSN1006-7108
DOI10.3969/j.issn.1006-7108.2016.11.008

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Summary:目的深入研究Ward区做为骨密度随访指标的临床意义。方法采用美国Norland XR-600双能X线骨密度仪,通过测定58例骨质疏松或骨量减少患者6个月内左股骨近端、正位腰椎、全身骨密度,观察股骨颈、Ward区、L2-4、全身骨密度（BMD）及骨矿含量与瘦体重的百分比（%TBMC/FFM）随时间的变化规律及临床特点;通过测定58例患者血钙、血磷、碱性磷酸酶等生化指标,分析其与骨密度的相关性。结果 1所有患者全身BMD降低,%TBMC/FFM低于5%或为正常低值。2服药治疗组6个月后Ward区BMD显著增加,P=0.0028,P〈0.05,差异有统计学意义;股骨颈、L2-4、全身BMD、%TBMC/FFM变化量的P值均大于0.05,差异无统计学意义;未服药组所有观测部位BMD变化均无统计学意义（P〉0.05）。3所有患者血钙、血磷、碱性磷酸酶（ALP）等生化指标无明显改变（P〉0.05）。结论 Ward区对骨密度变化敏感性高,做为骨质疏松患者的临床随访指标,优于其他部位的骨密度测量。
Bibliography:SUN Yun1, MA Zhaokun2 , PAN Keqin1 , NIE Qingdong3 , WEI Kedao4 , WANG Jianchao4（ 1. Department of Radiology, Beijing 100084; 2. Department of Orthopedics, Beijing 100084; 3. Department of laboratory, Hospital of Tsinghua University, Beijing 100084; 4. Chinese Center for Disease Control and Prevention of Radiation Protection and Nuclear Safety, Beijing 100084, China）
Bone mineral density; Ward region; X-ray
11-3701/R
Objective To further study the clinical significance of Ward region as a bone mineral density（ BMD） followup index. Me thods BMD of the femoral neck,Ward region,L2-4,whole body,and the ratio of bone mineral content and lean body mass percentage（ % TBMC / FFM） with time in 58 cases of osteoporosis was determined using dual-energy X-ray absorptiometry（ DXA,Norland XR-600） in 6 months. Serum levels of calcium,phosphorus,and alkaline phosphatase were examined. The correlation between them and BMD was analyzed. Re sults 1） The whole body BMD decreased and % TBMC / FFMwas lower than 5% or lower-normal val
ISSN:1006-7108
DOI:10.3969/j.issn.1006-7108.2016.11.008