中老年人腹主动脉钙化与腰椎骨密度的相关性研究

目的研究中老年人腹主动脉钙化（AAC）与腰椎定量CT（QCT）骨密度（BMD）的相关性。方法纳入2013年至2016年间招募的593名40-80岁（男性230人,女性363人）的健康志愿者测量受检者身高、体质量、腰围,计算体重指数（BMI）;进行腰椎QCT骨密度测量,将原始图像传至图像后处理工作站,采用Mindways QCT pro软件,分别测量L1-3椎体骨密度。应用Image J软件测量腹主动脉钙化面积比。结果男、女性AAC患病率分别约为45.65%、28.37%;与无AAC组比较,男性、女性AAC组年龄更大,并且与腰椎BMD的差异均有统计学意义（P均〈0.05）;男女腰椎BMD均与年龄...

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Bibliographic Details
Published in中国骨质疏松杂志 Vol. 23; no. 12; pp. 1574 - 1578
Main Author 刘红敏;程晓光;王玲;杜霞;焦俊
Format Journal Article
LanguageChinese
Published 贵州医科大学第一附属医院放射科,贵州贵阳,550004%北京积水潭医院放射科,北京,100035 2017
Subjects
定量CT（QCT）
年龄
腰椎骨密度（BMD）
腹主动脉钙化
骨质疏松
腰椎骨密度(BMD)
骨质疏松
Osteoporosis
腹主动脉钙化
定量CT(QCT)
Bone mineral density (BMD)
Quantitative computed tomography (QCT)
年龄
Age
Abdominal aortic calcification
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ISSN1006-7108
DOI10.3969/j.issn.1006-7108.2017.12.008

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Summary:目的研究中老年人腹主动脉钙化（AAC）与腰椎定量CT（QCT）骨密度（BMD）的相关性。方法纳入2013年至2016年间招募的593名40-80岁（男性230人,女性363人）的健康志愿者测量受检者身高、体质量、腰围,计算体重指数（BMI）;进行腰椎QCT骨密度测量,将原始图像传至图像后处理工作站,采用Mindways QCT pro软件,分别测量L1-3椎体骨密度。应用Image J软件测量腹主动脉钙化面积比。结果男、女性AAC患病率分别约为45.65%、28.37%;与无AAC组比较,男性、女性AAC组年龄更大,并且与腰椎BMD的差异均有统计学意义（P均〈0.05）;男女腰椎BMD均与年龄呈负相关（r=-0.49、r=-0.73,P〈0.05）,与BMI均无明显相关性（r=0.02、r=0.01,P〉0.05）;男、女性AAC均与年龄呈正相关（r=0.39、r=0.42,P〈0.05）,与BMI均无明显相关性（r=-0.03、r=-0.03,P〉0.05）;男性BMD与AAC无明显相关性（P=0.15）,女性BMD与AAC呈低度负相关（r=-0.32,P〈0.05）,校正年龄以后,女性BMD与AAC也无明显相关性（P=0.08）。结论年龄为腹主动脉钙化和骨质疏松发病的共同独立的危险因素,校正年龄后,男性、女性腰椎BMD与AAC均无显著相关性。
Bibliography:Osteoporosis; Abdominal aortic calcification; Bone mineral density （BMD）; Quantitative computed tomography （QCT） ; Age
11-3701/R
Objective To investigate the relationship between abdominal aortic calcification and bone mineral density （BMD） of the lumbar spine in the elderly population. Methods Totally 593 healthy volunteers （230 men and 363 women）, aged 40 to 80 years, were recruited from 2013 to 2016. Height, weight and waist circumference were measured, and body mass index （BMI） was calculated. Quantitative computed tomography （QCT） measurements were conducted and the original images were transmitted to the image post processing workstation. Using Mindways QCT Pro software, vertebral bone mineral density of L1-3 was measured. Using ImageJ software, abdominal aortic calcification was measured. Results The prevalence of AAC in male and female was 45.65% and 28.37%, respectively. Men and Women with AAC were older and had significantly lower lumber spine BMD than subjects without AAC （P〈0.05）. The correlation of
ISSN:1006-7108
DOI:10.3969/j.issn.1006-7108.2017.12.008