Metal nanoparticles synthesis through natural phenolic acids

• Published in: IET nanobiotechnology Vol. 13; no. 8; pp. 771 - 777
• Main Authors: Amini, Seyed Mohammad, Akbari, Abolfazl
• Format: Journal Article
• Language: English
• Published: United States The Institution of Engineering and Technology 01.10.2019; John Wiley & Sons, Inc; Wiley
• Subjects: adsorption; Amino acids; Antioxidants; Antioxidants - chemical synthesis; Antioxidants - pharmacology; biomedical applications; biomedical materials; bio‐inspired materials; efficient green synthesis techniques; Green Chemistry Technology - methods; Health aspects; Humans; Hydroxybenzoates - pharmacology; medicine; metal ion bioreduction; Metal Nanoparticles - chemistry; metal nanoparticles synthesis; metallic oxide nanoparticles; nanofabrication; nanomaterial synthesis; nanomedicine; Nanoparticles; natural phenolic acids; organic compounds; phenolic acids surface adsorption; phytochemical synthesis; Plant Extracts - pharmacology; plant‐derived phenolic acids; reducing agents; Review; Review Article; therapeutic agents; toxicity; Type 2 diabetes; toxicity; adsorption; antioxidants; reducing agents; natural phenolic acids; metal nanoparticles synthesis; nanomaterial synthesis; nanofabrication; nanomedicine; metallic oxide nanoparticles; plant-derived phenolic acids; medicine; therapeutic agents; efficient green synthesis techniques; bio-inspired materials; nanoparticles; metal ion bioreduction; biomedical applications; biomedical materials; organic compounds; phytochemical synthesis; phenolic acids surface adsorption
• ISSN: 1751-8741; 1751-875X; 1751-875X
• DOI: 10.1049/iet-nbt.2018.5386

For being applied in medicine as therapeutic agents, nanostructures need to be biocompatible and eco-friendly. Plant-derived phenolic acids have been utilised for green synthesis of metallic or metallic oxide nanoparticles (NPs). The phenolic acids play role as both reducing agents and stabilisers in the process of NPs synthesis. Many experiments have been dedicated to develop efficient green synthesis techniques for producing metal NPs. Using phenolic acids represents a reproducible, simple, profitable, and cost-effective strategy to synthesise metal NPs. As a phytochemical for metal NPs synthesis, phenolic acids are antioxidants that represent many health benefits. However, limited studies have been dedicated to the synthesis and characterisation of NPs produced by phenolic acids. Thus, this review focused on phenolic acids mediated nanomaterial synthesis and its biomedical applications. It should be noted the mechanism of metal ion bioreduction, phenolic acids surface adsorption, characterisation, and toxicity of metal NPs made with different phenolic acids have been discussed in this review.