常规MR征象在鉴别单发大脑胶质瘤级别中的价值

目的评估单发大脑胶质瘤常规核磁共振（MR）检查征象在评价大脑胶质瘤高低级别中的价值。方法回顾性分析有手术病理结果的218例单发大脑胶质瘤患者,分为低级别组（134例）和高级别组（84例）。采用t检验、卡方检验和逻辑回归分析评价患者年龄、性别及MR征象（包括接触脑室下区（subventricular zone,SVZ）、不均匀性、肿瘤边界、坏死囊变、出血、跨越中线、占位效应、水肿程度、强化体积、强化不均匀性）在高低级别胶质瘤组间差异及相关性。结果高、低级别胶质瘤组间,年龄有统计学差异（P〈0.001）,性别未见统计学差异（P=0.864）。在MR征象中,接触SVZ（P=0.011）、肿瘤不均匀性...

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Published in西安交通大学学报（医学版） Vol. 38; no. 6; pp. 866 - 871
Main Author 王蓉 郑婕 杜永浩 刘哲 杨健
Format Journal Article
LanguageChinese
Published 西安交通大学第一附属医院医学影像科,陕西西安,710061%西安交通大学第一附属医院临床研究中心,陕西西安,710061 2017
Subjects
大脑胶质瘤
核磁共振（MR）
病理分级
pathological grading
大脑胶质瘤
cerebral glioma
病理分级
magnetic resonance (MR)
核磁共振(MR)
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ISSN1671-8259
DOI10.7652/jdyxb201706016

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Summary:目的评估单发大脑胶质瘤常规核磁共振（MR）检查征象在评价大脑胶质瘤高低级别中的价值。方法回顾性分析有手术病理结果的218例单发大脑胶质瘤患者,分为低级别组（134例）和高级别组（84例）。采用t检验、卡方检验和逻辑回归分析评价患者年龄、性别及MR征象（包括接触脑室下区（subventricular zone,SVZ）、不均匀性、肿瘤边界、坏死囊变、出血、跨越中线、占位效应、水肿程度、强化体积、强化不均匀性）在高低级别胶质瘤组间差异及相关性。结果高、低级别胶质瘤组间,年龄有统计学差异（P〈0.001）,性别未见统计学差异（P=0.864）。在MR征象中,接触SVZ（P=0.011）、肿瘤不均匀性（P〈0.001）、坏死囊变（P=0.037）、水肿程度（P=0.017）、占位效应（P=0.009）、肿瘤边界（P〈0.001）以及强化体积（P〈0.001）在两组间有统计学差异。多因素逻辑回归分析显示,年龄、肿瘤坏死囊变、肿瘤边界以及强化程度是高级别胶质瘤的阳性预测值。结论常规MR征象可用于鉴别大脑胶质瘤的高低级别;患者年龄越大、肿瘤坏死囊变越严重、肿瘤边界不清和强化体积越大的,为高级别胶质瘤的可能性越大。
Bibliography:Objective To evaluate the value of conventional MRI in determining high-or low-grade solitary cerebral glioma.Methods We divided 218 patients with solitary cerebral glioma confirmed by surgical pathology into low-grade group（n=134）and high-grade group（n=84）.MRI features include the following：in contact with subventricular zone（SVZ）,tumor heterogeneity,tumor boundary,necrosis,hemorrhage,crossing midline,occupying effect,peritumoral edema,volume of enhancement,and enhanced inhomogeneity.The t-test,chi-square test and logistic regression analysis were used to evaluate the differences in age,gender and magnetic resonance imaging between the high-and low-grade glioma groups.MRI findings were then correlated with grade of gliomas.Results There was a significant difference in age between the two groups（P〈0.001）.There was no significant difference in men and women between the two groups（P=0.864）.Seven out of ten MRI findings were identified to be significantly different between high-and low-grade groups.They were SVZ
ISSN:1671-8259
DOI:10.7652/jdyxb201706016