Retinal vasculitis and skin ulcer preceding Budd-Chiari syndrome in a patient with Behcet's disease

• Published in: Indian journal of ophthalmology Vol. 68; no. 9; pp. 2015 - 2017
• Main Authors: Bhatia, Priyavrat, Sen, Alok, Kohli, Gaurav, Shenoy, Pratik
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer India Pvt. Ltd 01.09.2020; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Wolters Kluwer - Medknow; Wolters Kluwer Medknow Publications
• Subjects: Adult; Ascites; Behcet Syndrome - complications; Behcet Syndrome - diagnosis; behcet's disease; Behcet's syndrome; Budd-Chiari syndrome; Budd-Chiari Syndrome - diagnosis; Budd-Chiari Syndrome - etiology; Case Reports; Case studies; Diagnosis; Drug therapy; Female; hla b-52; Humans; Retina; Retinal diseases; retinal vasculitis; Retinal Vasculitis - diagnosis; Retinal Vasculitis - etiology; Skin diseases; Skin lesions; Skin Ulcer; Thrombosis; Ulcers; Uveitis; Vasculitis; Vein & artery diseases; Vena Cava, Inferior; venous ulcer; Young Adult; India; HLA B-52; Behcet's disease; retinal vasculitis; Budd-Chiari syndrome; venous ulcer
• ISSN: 0301-4738; 1998-3689; 1998-3689
• DOI: 10.4103/ijo.IJO_1338_20

Behcet's disease (BD) is a multisystem disorder with a classical triad of recurrent oral ulcers, genital ulcers, and uveitis. It involves both arterial and venous system which can lead to life-threatening complications. Both superficial and deep venous systems can be involved leading to peripheral skin lesions and devastating complications like cerebral venous thrombosis and Budd-Chiari syndrome (BCS). This report describes a case of an HLA B-52 positive BD in a 22-year-old woman who presented with retinal vasculitis and venous ulcer on the foot and later on developed ascites due to obstruction of supra-hepatic inferior vena cava (BCS). This report highlights the fact that BCS can develop in patients of BD and every ophthalmologist should be aware of this life-threatening complication while they are treating these patients, as timely diagnosis and intervention can prevent mortality.