复方补肾活血颗粒对肾虚血瘀证绝经后非老年骨质疏松症患者视觉模拟评分和骨密度影响的临床观察

目的观察复方补肾活血颗粒对绝经后非老年骨质疏松症患者视觉模拟评分（Visual Analog Scale,VAS）和骨密度（Bone Mineral Density,BMD）的影响。方法研究对象选自2015年6月-2015年12月在本院诊治的肾虚血瘀证绝经后非老年骨质疏松症患者60例,将患者按照随机函数随机分为两组（对照组和治疗组）,每组30例。两组均给予一般治疗,对照组予仙灵骨葆胶囊治疗,治疗组予复方补肾活血颗粒。两组观察时限均为6个月,治疗前后需按照研究方案定期计算中医证候积分,BMD和VAS等指标。结果临床观察表明,复方补肾活血颗粒治疗组中医证候有效率为90%,对照组为60%,与对照组相...

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Bibliographic Details
Published in中国骨质疏松杂志 Vol. 24; no. 1; pp. 98 - 101
Main Author 赵进东;舒仪琼;刘剑;李家云;李艳;王燕俐;邸维莹;洪文惠;胡秀;方朝晖
Format Journal Article
LanguageChinese
Published 新安医学教育部重点实验室,安徽合肥230038%安徽中医药大学第一附属医院内分泌科,安徽合肥,230031 2018
安徽中医药大学第一附属医院内分泌科,安徽合肥230031
Subjects
复方补肾活血颗粒
绝经后非老年骨质疏松症
肾虚血瘀证
视觉模拟评分
骨密度
视觉模拟评分
Visual analog scale
复方补肾活血颗粒
绝经后非老年骨质疏松症
肾虚血瘀证
Kidney deficiency blood stasis syndrome
Compound kidney-invigorating granule
骨密度
Bone mineral density
Postmenopausal osteoporosis
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ISSN1006-7108
DOI10.3969/j.issn.1006-7108.2018.01.022

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Summary:目的观察复方补肾活血颗粒对绝经后非老年骨质疏松症患者视觉模拟评分（Visual Analog Scale,VAS）和骨密度（Bone Mineral Density,BMD）的影响。方法研究对象选自2015年6月-2015年12月在本院诊治的肾虚血瘀证绝经后非老年骨质疏松症患者60例,将患者按照随机函数随机分为两组（对照组和治疗组）,每组30例。两组均给予一般治疗,对照组予仙灵骨葆胶囊治疗,治疗组予复方补肾活血颗粒。两组观察时限均为6个月,治疗前后需按照研究方案定期计算中医证候积分,BMD和VAS等指标。结果临床观察表明,复方补肾活血颗粒治疗组中医证候有效率为90%,对照组为60%,与对照组相比,疗效明显优于对照组（P〈0.01）。治疗组中医证候积分为7.96±3.86分,对照组为10.16±3.85分,两组比较具有统计学差异。治疗后治疗组BMD和VAS分别为2.24±0.55 g/cm^2、1.96±1.47分,对照组为2.50±0.41 g/cm^2、2.86±1.79分,治疗组改善情况优于对照组。结论复方补肾活血颗粒能显著改善绝经后非老年骨质疏松症患者中医临床症状、BMD和VAS,未见不良事件的发生,复方补肾活血颗粒治疗绝经后非老年骨质疏松症是安全有效的。
Bibliography:Postmenopausal osteoporosis; Kidney deficiency blood stasis syndrome; Compound kidney-invigorating granule; Bone mineral density; Visual analog scale
11-3701/R
Objective To observe the effect of compound kidney-invigorating granule on visual analog scale（VAS） and bone mineral density（BMD） in postmenopausal non-senile osteoporosis patients.Methods Sixty postmenopausal non-senile patients with osteoporosis and kidney deficiency and blood stasis diagnosed and treated in our hospital were selected from June 2015 to December 2015.The patients were randomly divided into two groups（control group and treatment group）,with 30 cases in each group.Patients in both groups received general treatment.The patients in control group was received Xianlinggubao capsule.The patients in treatment group received compound kidney-invigorating granule.The observation period was six months for both groups.Before and after treatment,the TCM syndrome integrals,BMD,and VAS were calculated regularly according to the research program.Results
ISSN:1006-7108
DOI:10.3969/j.issn.1006-7108.2018.01.022