肝细胞癌癌前异型增生结节的研究现状

R735.7; 异型增生结节(DN)是肝细胞癌(HCC)癌前病变向HCC演变的重要阶段,具有极高的癌变风险.依据细胞异型性的不同,DN可分为低度异型增生结节(LGDN)和高度异型增生结节(HGDN),总结了LGDN与HGDN的病理特点、影像学特征及生物标志物,简述了DN恶变为HCC的风险大小,指出应当提高临床医师对于HCC癌前病变DN的认识,通过对DN的筛查发现恶变风险高的结节并进行干预,以防止HCC的发生....

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Bibliographic Details
Published in临床肝胆病杂志 Vol. 33; no. 5; pp. 974 - 978
Main Author 焦俊喆 李京涛 闫曙光 魏海梁 鞠迪 宋艺君 常占杰
Format Journal Article
LanguageChinese
Published 陕西中医药大学,陕西咸阳,712000%陕西中医药大学附属医院,陕西咸阳,712046 2017
Subjects
异型增生结节
生物学标记
病理状态,体征和症状
癌,肝细胞
综述
dysplastic nodule
病理状态,体征和症状
review
biological markers
异型增生结节
综述
生物学标记
carcinoma,hepatocellular
pathological conditions,signs and symptoms
癌,肝细胞
Online AccessGet full text
ISSN1001-5256
DOI10.3969/j.issn.1001-5256.2017.05.039

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Summary:R735.7; 异型增生结节(DN)是肝细胞癌(HCC)癌前病变向HCC演变的重要阶段,具有极高的癌变风险.依据细胞异型性的不同,DN可分为低度异型增生结节(LGDN)和高度异型增生结节(HGDN),总结了LGDN与HGDN的病理特点、影像学特征及生物标志物,简述了DN恶变为HCC的风险大小,指出应当提高临床医师对于HCC癌前病变DN的认识,通过对DN的筛查发现恶变风险高的结节并进行干预,以防止HCC的发生.
Bibliography:JIAO Junzhe, LI Jingtao, YAN Shuguang, et al. （ Shaanxi University of Chirtese Medicine, Xianyang, Shaanxi 712000, China）
carcinonm, hepatocellular; dysplastic nodule ; pathoological conditions, signs and symptoms ; biological mmkers ; review
Dysplastic nodule （DN） is an important stage for precancerous hepatocellular carcinoma （HCC） lesions progressing to HCC and has a velT high risk of canceration. According to the difference in atypia, DN is classified into low -grade DN （LGDN） and high -grade DN （HGDN）. This article summarizes the pathological features, radiological features, and bimnarkers of LGDN and HGDN, briefly de- scribes the risk of the canceration of DN into HCC, and points out that il is necessary to enhance the knowledge of DN, the precancerous IICC lesions, in clinical physicians. DN screening to identify nodules with a high risk of cauceration and related intervention help to prevent the development of HCC.
22-1108/R
ISSN:1001-5256
DOI:10.3969/j.issn.1001-5256.2017.05.039