Cost-effectiveness of a technology-supported multimodal prehabilitation program in moderate-to-high risk patients undergoing lung cancer resection: randomized controlled trial protocol

• Published in: BMC health services research Vol. 20; no. 1; pp. 207 - 6
• Main Authors: Barberan-Garcia, Anael, Navarro-Ripoll, Ricard, Sánchez-Lorente, David, Moisés-Lafuente, Jorge, Boada, Marc, Messaggi-Sartor, Monique, González-Vallespí, Laura, Montané-Muntané, Mar, Alsina-Restoy, Xavier, Campero, Betina, Lopez-Baamonde, Manuel, Romano-Andrioni, Barbara, Guzmán, Rudith, López, Antonio, Arguis, Maria Jose, Roca, Josep, Martinez-Palli, Graciela
• Format: Journal Article
• Language: English
• Published: London BioMed Central 12.03.2020; BioMed Central Ltd; BMC
• Subjects: Abstinence; Alcohol use; Behavior modification; Cancer therapies; Care and treatment; Chronic illnesses; Chronic obstructive pulmonary disease; Clinical trials; Cognitive behavioral therapy; Cognitive therapy; Control; Coping; Cost analysis; Economic aspects; Educational materials; Empowerment; Excision (Surgery); Exercise; Exercise training; Fitness training programs; Health Administration; Health care costs; Health Informatics; Health services; Healthcare needs and demand; Hospitals; Information management; Interval training; Intervention; Length of stay; Lung cancer; Malnutrition; Medical personnel; Medicine; Medicine & Public Health; Methods; Nursing Research; Nutritional optimization; Patient outcomes; Patients; Physical activity; Physical fitness; Prehabilitation; Preoperative care; Proteins; Public Health; Questionnaires; Smoking cessation; Study Protocol; Surgery; Thoracic surgery; Spain; Italy; Smoking cessation; Physical activity; Postoperative morbidity; Prehabilitation; Cognitive behavioral therapy; Exercise training; Nutritional optimization
• ISSN: 1472-6963; 1472-6963
• DOI: 10.1186/s12913-020-05078-9

Background Multimodal prehabilitation is a preoperative intervention with the objective to enhance cancer patients’ functional status which has been showed to reduce both postoperative morbidity and hospital length of stay in digestive oncologic surgery. However, in lung cancer surgery patients further studies with higher methodological quality are needed to clarify the benefits of prehabilitation. The main aim of the current protocol is to evaluate the cost-effectiveness of a multimodal prehabilitation program supported by information and communication technologies in moderate-to-high risk lung cancer patients undergoing thoracic surgery. Methods A Quadruple Aim approach will be adopted, assessing the prehabilitation program at the following levels: i) Patients’ and professionals’ experience outcomes (by means of standardized questionnaires, focus groups and structured interviews); ii) Population health-based outcomes (e.g. hospital length of stay, number and severity of postoperative complications, peak oxygen uptake and levels of systemic inflammation); and, iii) Healthcare costs. Discussion This study protocol should contribute not only to increase the scientific basis on prehabilitation but also to detect the main factors modulating service adoption. Trial registration NCT04052100 (August 9, 2019).