局部消融在肝细胞癌治疗中的应用

手术切除和肝移植被认为是肝细胞癌（HCC）根治性治疗手段,但仅有10%~20%的HCC患者能接受这些治疗。近些年来,射频消融、微波消融、冷冻消融及新近出现的不可逆电穿孔消融等局部治疗方法逐渐成为无法手术患者的替代治疗。除了局部控制肿瘤生长改善预后外,消融技术还有助于肿瘤降级以便二次切除。重点介绍了射频消融及联合其他治疗手段治疗HCC的进展,对射频消融与其他局部消融进行了比较,简述了智能导航技术在辅助消融中的应用,认为随着影像医学的发展以及其他相关领域的进步,未来消融技术在临床应用中将更加广泛。...

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Bibliographic Details
Published in临床肝胆病杂志 Vol. 32; no. 1; pp. 56 - 61
Main Author 朱晓黎 沈健
Format Journal Article
LanguageChinese
Published 苏州大学附属第一医院 介入科,江苏 苏州,215006 2016
Subjects
局部消融术
治疗
癌,肝细胞
局部消融术
治疗
carcinoma,hepatocellular
local ablation
therapy
癌,肝细胞
Online AccessGet full text
ISSN1001-5256
DOI10.3969/j.issn.1001-5256.2016.01.008

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Summary:手术切除和肝移植被认为是肝细胞癌（HCC）根治性治疗手段,但仅有10%~20%的HCC患者能接受这些治疗。近些年来,射频消融、微波消融、冷冻消融及新近出现的不可逆电穿孔消融等局部治疗方法逐渐成为无法手术患者的替代治疗。除了局部控制肿瘤生长改善预后外,消融技术还有助于肿瘤降级以便二次切除。重点介绍了射频消融及联合其他治疗手段治疗HCC的进展,对射频消融与其他局部消融进行了比较,简述了智能导航技术在辅助消融中的应用,认为随着影像医学的发展以及其他相关领域的进步,未来消融技术在临床应用中将更加广泛。
Bibliography:ZHU Xiaoli, SHEN Jian. （ Department of lnterventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, China）
Hepatocellular carcinoma （HCC） is a common malignant tumor in the world, and surgical resection and liver transplantation are two radical treatment modalities, but only 10% - 20% of all patients can receive such treatments. In recent years, local therapies including radiofrequency ablation, microwave ablation, cryoablation, and the irreversible electroporation ablation which appeared recently have gradually become the alternative therapies for the patients who are unable to undergo surgery. In addition to local tumor growth control and im- provement in survival outcomes, the ablation technology also helps to downgrade tumor for secondary resection. This article focuses on the re- search progress in radiofrequency ablation alone and in combination with other therapies in the treatment of HCC, compares radiofrequency ablation with other local ablative therapies, and
ISSN:1001-5256
DOI:10.3969/j.issn.1001-5256.2016.01.008