绵羊肺炎支原体p113基因的序列分析及功能预测

采用多种软件对p113基因的相似性、跨膜结构、重复序列、信号肽、抗原表位等进行预测，并与同源序列进行比较分析．结果表明，p113基因是猪肺炎支原体黏附素基因p97的直系同源基因，并具有与P97蛋白R2区类似的特征性重复序列．通过综合比较分析，推测P113蛋白极可能是绵羊肺炎支原体的黏附素和膜表面免疫原．...

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Bibliographic Details
Published in华南农业大学学报 Vol. 34; no. 1; pp. 117 - 121
Main Author 杨发龙 张焕容 汤承 岳华
Format Journal Article
LanguageChinese
Published 西南民族大学生命科学与技术学院,四川成都,610041 2013
Subjects
p113基因
免疫原
绵羊肺炎支原体
黏附素
绵羊肺炎支原体
p113基因
黏附素
免疫原
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ISSN1001-411X

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Summary:采用多种软件对p113基因的相似性、跨膜结构、重复序列、信号肽、抗原表位等进行预测，并与同源序列进行比较分析．结果表明，p113基因是猪肺炎支原体黏附素基因p97的直系同源基因，并具有与P97蛋白R2区类似的特征性重复序列．通过综合比较分析，推测P113蛋白极可能是绵羊肺炎支原体的黏附素和膜表面免疫原．
Bibliography:Mycoplasma ovipneumoniae ; p113 gene; adhesin ; immunogen
44-1110/S
YANG Falong, ZHANG Huanrong, TANG Cheng, YUE Hua （ College of Life Science and Technology, Southwest University for Nationalities, Chengdu 610041, China）
The aim of this paper is to conduct a bioinformatics analysis for p113 gene of Mycoplasma ovi- prteumoniae and further predict its functions. Using several softwares, homology of p113 gene with other genes was calculated and trans-membrane structure, repeat sequence, signal peptide and epitodes were predicted. The results revealed that p113 was an orthologous of Mycoplasma hyopneumoniae adhesin gene p97 which shared similar R2 repeat sequence. Overall analysis leads to the prediction that P113 protein is one of the important adhesins and membrane immunogens.
ISSN:1001-411X