中国高颅压患者视神经鞘直径的诊断价值

目的确定视神经鞘直径（optic nerve sheath diameter,ONSD）评估颅内压（intracranial pressure,ICP）增高的诊断标准并研究其相关影响因素。方法本研究为双盲横断面研究,收集2013年3月-12月可疑高ICP需要进行腰椎穿刺测量脑脊液压力的患者为研究对象,记录患者的个体相关信息及脑脊液压力值,分为ICP正常组及增高组,比较两组患者相关因素的差异。运用接受者操作特性曲线（receiver operating characteristic,ROC）确定高ICP的ONSD最佳诊断值。结果共收录了279例患者,其中包括101例高ICP患者。比较显示,ONS...

Full description

Saved in:
Bibliographic Details
Published in中国卒中杂志 Vol. 11; no. 7; pp. 563 - 569
Main Author 王丽娟 冯良枢 姚燕 王玉芝 陈盈 冯加纯 邢英琦
Format Journal Article
LanguageChinese
Published 130021,长春吉林大学第一医院神经内科和神经科学中心%吉林大学公共卫生学院流行病与卫生统计学教研室 2016
Subjects
无创
视神经鞘
超声
高颅压
高颅压
Elevated intracranial pressure
无创
Ultrasonography
Optic nerve sheath
视神经鞘
超声
Noninvasive
Online AccessGet full text
ISSN1673-5765
DOI10.3969/j.issn.1673-5765.2016.07.008

Cover

More Information
Summary:目的确定视神经鞘直径（optic nerve sheath diameter,ONSD）评估颅内压（intracranial pressure,ICP）增高的诊断标准并研究其相关影响因素。方法本研究为双盲横断面研究,收集2013年3月-12月可疑高ICP需要进行腰椎穿刺测量脑脊液压力的患者为研究对象,记录患者的个体相关信息及脑脊液压力值,分为ICP正常组及增高组,比较两组患者相关因素的差异。运用接受者操作特性曲线（receiver operating characteristic,ROC）确定高ICP的ONSD最佳诊断值。结果共收录了279例患者,其中包括101例高ICP患者。比较显示,ONSD是ICP的独立预测因素（P〈0.001）,不受性别、年龄、体质指数（body mass index,BMI）、头围、腰围、高血压和病因分型的影响。ONSD能够有效准确地评估高ICP。运用超声检测ONSD诊断高ICP的最佳临界值是4.1 mm（敏感度95%,特异度92%）。结论我国高ICP患者的ONSD的诊断值比白种人低,因此建议检测ONSD评估高ICP时应该注意种族差异。
Bibliography:11-5434/R
Ultrasonography of the optic nerve sheath diameter（ONSD） is a non-invasive and rapid method that might be helpful in the identification of increased intracranial pressure（ICP）. The use of an ONSD greater than 5 mm on ultrasound as an indicator of increased ICP in a Caucasian population has been studied. However, the cut-off point of this predictor in Chinese patients has not been established. Thus, we conducted this study to identify the ONSD criterion for the detection of elevated opening pressure on lumbar puncture（LP） in a Chinese population and to investigate the influencing factors. This study was a blind cross-sectional study. Patients who presented with suspected increased ICP were included. The opening pressure on LP of each participant was confirmed. We analyzed the clinical differences between the groups of patients with abnormal and normal opening pressures on LP. A receiver operating characteristic curve was constructed to determine the ONSD cut-off point for the identification of abnorma
ISSN:1673-5765
DOI:10.3969/j.issn.1673-5765.2016.07.008