中心静脉导管引流联合白细胞介素-2注射治疗肝性胸水患者21例疗效观察

目的观察中心静脉导管引流联合白细胞介素-2(IL-2)注射治疗肝性胸水的疗效。方法 40例肝性胸水患者随机分成治疗组(21例)和对照组(19例),两组患者均给予护肝、输白蛋白等支持治疗的基础上,对照组采用常规穿刺抽胸水治疗,治疗组则采用中心静脉导管留置胸腔引流管,完全排空胸水后,注入IL-2,观察两组患者的疗效及并发症情况。结果治疗组治疗总有效率为85.7%,对照组治疗总有效率为52.6%。两组比较差异有统计学意义(P〈0.05);治疗组的胸水消退的天数、平均住院费用以及住院天数均明显缩短(P〈0.05),并发症少。结论中心静脉导管联合IL-2治疗肝性胸水的疗效显著,值得临床推广。...

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Published in临床肝胆病杂志 Vol. 28; no. 8; pp. 616 - 617
Main Author 周年兰 陈超伍 向晓星
Format Journal Article
LanguageChinese
Published 扬州大学临床医学院附属医院苏北人民医院消化内科,江苏扬州,225001 2012
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ISSN1001-5256

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Summary:目的观察中心静脉导管引流联合白细胞介素-2(IL-2)注射治疗肝性胸水的疗效。方法 40例肝性胸水患者随机分成治疗组(21例)和对照组(19例),两组患者均给予护肝、输白蛋白等支持治疗的基础上,对照组采用常规穿刺抽胸水治疗,治疗组则采用中心静脉导管留置胸腔引流管,完全排空胸水后,注入IL-2,观察两组患者的疗效及并发症情况。结果治疗组治疗总有效率为85.7%,对照组治疗总有效率为52.6%。两组比较差异有统计学意义(P〈0.05);治疗组的胸水消退的天数、平均住院费用以及住院天数均明显缩短(P〈0.05),并发症少。结论中心静脉导管联合IL-2治疗肝性胸水的疗效显著,值得临床推广。
Bibliography:ZHOU Nian - lan, CHEN Chao - wu, XIANG Xiao - xing. ( Department of Gastroenterology, Subei People' s Hospital of Jiangsu Province af- filiated to the Hospital of Yangzhou University, Yangzhou, Jiangsu 225001, China)
catheterization, central venous ; interleukin - 2 ; hydrothorax; liver cirrhosis
Objective To observe the curative effect of central venous catheter when combined with interleukin (IL) - 2 treatment for he- patic hydrothorax. Methods Thirty - three patients with hepatic hydrothorax were randomly assigned to an experimental treatment group ( n = 17 ) or a control treatment group (n = 16). The experimental group received pleural effusion with continuous drainage by central venous catheter, while the control group was relieved of pleural effusion by conventional puncture. Both groups were administered IL - 2 injection into the thoracic cavity after evacuation of pleural effusion. All patients were administered post - operative therapy, including albumin, to protect the liver. The curative effect and c
ISSN:1001-5256