外周血白细胞端粒长度与心脑血管疾病风险的研究进展

目前的研究显示端粒的长度与人类的衰老、疾病密切相关。研究显示端粒的长度与动脉粥样硬化相关。在心脑血管疾病的研究中发现外周血白细胞端粒缩短与心血管疾病风险正相关,但与脑血管疾病的关系尚有争议。本文就外周血白细胞端粒长度与心脑血管疾病之间的关系进行综述。...

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Bibliographic Details
Published in中国卒中杂志 Vol. 11; no. 1; pp. 82 - 86
Main Author 李静 张梅 张伟丽
Format Journal Article
LanguageChinese
Published 232007,淮南 安徽省蚌埠医学院附属淮南市第一人民医院神经内科%中国医学科学院阜外心血管病医院心血管疾病国家重点实验室 2016
Subjects
动脉粥样硬化
卒中
端粒长度
卒中
端粒长度
Stroke
动脉粥样硬化
Telomere length
Atherosclerosis
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ISSN1673-5765
DOI10.3969/j.issn.1673-5765.2016.01.014

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Summary:目前的研究显示端粒的长度与人类的衰老、疾病密切相关。研究显示端粒的长度与动脉粥样硬化相关。在心脑血管疾病的研究中发现外周血白细胞端粒缩短与心血管疾病风险正相关,但与脑血管疾病的关系尚有争议。本文就外周血白细胞端粒长度与心脑血管疾病之间的关系进行综述。
Bibliography:11-5434/R
LI Jing, ZHANG Mei, ZHANG Wei-Li. （Department of Neurology, the First People＇s Hospital of Huainan Affiliated to Bengbu Medical College in Anhui Provinee, Huainan 232007, China）
Telomere length; Atherosclerosis; Stroke
Accumulating studies have showed the association between telomere length and aging or diseases. Studies have showed that telomere length was associated with atherosclerosis. During the studies on cardiovascular and cerebrovascular diseases, the positive relationship between peripheral blood leukocyte telomere shortening and the risk of cardiovascular diseases was found, but the relationship between telomere length and cerebrovascular diseases was controversial. In this paper, the relationship between circulating leukocyte telomere length and cardiovascular or cerebrovascular diseases was reviewed.
ISSN:1673-5765
DOI:10.3969/j.issn.1673-5765.2016.01.014