In Situ Patterning of Microfluidic Networks in 3D Cell-Laden Hydrogels

Focalized short‐pulsed lasers have sufficient power to generate micrometer‐sized cavities in various hydrogels. An in situ technique based on laser ablation to fabricate intricate microfluidic networks in biocompatible gels without manual handling is presented. This method is fully compatible with 3...

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Bibliographic Details
Published inAdvanced materials (Weinheim) Vol. 28; no. 34; pp. 7450 - 7456
Main Authors Brandenberg, Nathalie, Lutolf, Matthias P.
Format Journal Article
LanguageEnglish
Published Germany Blackwell Publishing Ltd 01.09.2016
Subjects
Biology
Biotechnology
Holes
Hydrogels
Lasers
Manuals
microfabrication
Microfluidics
Networks
short-pulsed lasers
tissue engineering
microfabrication
tissue engineering
hydrogels
microfluidics
short-pulsed lasers
Online AccessGet full text
ISSN0935-9648
1521-4095
1521-4095
DOI10.1002/adma.201601099

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Summary:Focalized short‐pulsed lasers have sufficient power to generate micrometer‐sized cavities in various hydrogels. An in situ technique based on laser ablation to fabricate intricate microfluidic networks in biocompatible gels without manual handling is presented. This method is fully compatible with 3D cell culture and opens up unprecedented opportunities for cell biology, developmental biology, and stem‐cell‐based tissue engineering.
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ArticleID:ADMA201601099
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0935-9648
1521-4095
1521-4095
DOI:10.1002/adma.201601099