Arterial stiffness and hypertension

• Published in: Clinical hypertension Vol. 24; no. 1; pp. 17 - 3
• Main Author: Oh, Young S.
• Format: Journal Article
• Language: English
• Published: London BioMed Central 01.12.2018; BioMed Central Ltd; BMC; 대한고혈압학회
• Subjects: Aerobics; Aging; Angiology; Animals; Aortic stiffness; Arterial; Blood pressure; Cardiology; Cardiovascular disease; Diabetes; Diet; Enzymes; Exercise; Heart; Hormone replacement therapy; Hypertension; Medicine; Medicine & Public Health; Metabolism; Mortality; Obesity; Older people; Physical fitness; Prevention; Review; Risk factors; Vascular biology; Vascular diseases; Veins & arteries; Young adults; 내과학; Hypertension; Cardiovascular disease; Arterial; Vascular biology; Aortic stiffness
• ISSN: 2056-5909; 1342-2154; 2635-6325; 2056-5909
• DOI: 10.1186/s40885-018-0102-8

Measures of the functional and structural properties of blood vessels can be used to assess preclinical stage of vascular disorders. Recent experimental and population studies show that arterial stiffening precedes development of high blood pressure, and can be used to predict future cardiovascular events. Arterial stiffness was also shown to be reversible in several experimental models of various conditions. Since reversing arterial stiffness could prevent development of hypertension and other clinical conditions, understanding the biological mechanisms of arterial stiffening and investigating potential therapeutic interventions to modulate arterial stiffness are important research topics. For research and application in general clinical settings, it is an important step to develop reliable devices and a standardized arterial stiffness measurement protocol.