舒张性和收缩性心衰患者的临床表现差异分析
目的:比较舒张性心功能衰竭(心衰)和收缩性心衰患者在临床表现及危险因素方面的差异。方法将2088例心衰患者按左室射血分数(EF)分为舒张性心衰组(EF≥0.45,1356例)和收缩性心衰组(EF<0.45,732例),比较2组的临床资料,分析影响2种心衰类型的相关因素。结果与收缩性心衰组相比,舒张性心衰组的平均年龄更大,女性及高血压的比例更高,但低蛋白血症、贫血、肾功能不全、高尿酸血症的比例更低,且以心功能Ⅰ、Ⅱ级为主;收缩压、白蛋白、前白蛋白、胆固醇、血钠、血氯水平更高,但心率更慢,肌酐、血尿酸、血钾、脑钠肽水平更低。与收缩性心衰组相比,舒张性心衰组的左室舒末容积、左室缩末容积较低,RAS阻...
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          | Published in | 天津医药 Vol. 43; no. 1; pp. 68 - 71 | 
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| Main Author | |
| Format | Journal Article | 
| Language | Chinese | 
| Published | 
            中国医科大学附属盛京医院心内科,辽宁沈阳 邮编,110004
    
        2015
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| Subjects | |
| Online Access | Get full text | 
| ISSN | 0253-9896 | 
| DOI | 10.3969/j.issn.0253-9896.2015.01.018 | 
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| Summary: | 目的:比较舒张性心功能衰竭(心衰)和收缩性心衰患者在临床表现及危险因素方面的差异。方法将2088例心衰患者按左室射血分数(EF)分为舒张性心衰组(EF≥0.45,1356例)和收缩性心衰组(EF<0.45,732例),比较2组的临床资料,分析影响2种心衰类型的相关因素。结果与收缩性心衰组相比,舒张性心衰组的平均年龄更大,女性及高血压的比例更高,但低蛋白血症、贫血、肾功能不全、高尿酸血症的比例更低,且以心功能Ⅰ、Ⅱ级为主;收缩压、白蛋白、前白蛋白、胆固醇、血钠、血氯水平更高,但心率更慢,肌酐、血尿酸、血钾、脑钠肽水平更低。与收缩性心衰组相比,舒张性心衰组的左室舒末容积、左室缩末容积较低,RAS阻断剂和β受体阻断剂使用率更低,他汀类药物使用率更高。Logistic多因素回归分析发现,性别、高血压对舒张性心衰影响更强;低蛋白血症、高尿酸血症则对收缩性心衰影响更强。结论舒张性心衰和收缩性心衰存在诸多差异,不同类型的心衰需采取不同的诊治及预防方案。 | 
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| Bibliography: | YU Tongtong, LIU Shuangshuang, WANG Jingjing, WANG Chuanhe, HAN Su, SUN Zhijun (Department of Cardiology, Shengjing Hospital of China Medical University, Shenyang 110004, China) heart failure,diastolic;heart failure,systolic;clinical characteristics;risk factors Objective To analyze the differences in clinical characteristics and risk factors in patients with diastolic heart failure and systolic heart failure. Methods A total of 2 088 patients with heart failure were divided into two groups, diastolic heart failure group (EF≥0.45,n=1 356) and systolic heart failure group (EF〈0.45,n=732), according to ejection fraction (EF). The clinical features and related factors affecting the two types of heart failure were compared between two groups. Results There were higher age, higher proportion of women and higher proportion of hypertensive patients in dia?stolic heart failure group than those of systolic heart failure group, but lower rates of hypoalbuminemia, anemia, renal insuffi?ciency and hyperuricimia. There was  | 
| ISSN: | 0253-9896 | 
| DOI: | 10.3969/j.issn.0253-9896.2015.01.018 |