基于介电电泳的微流控细胞分离芯片的研究进展

细胞分离技术是细胞分选和细胞种群纯化的重要手段，在生物、医学、农业、环境等许多领域都有重要的应用，是当前生化分析领域的国际研究热点。本文介绍了基于介电电泳的微流控细胞分离芯片的研究现状，阐述了介电电泳的工作原理，并依据细胞尺寸、电极形状、外加信号方式等影响细胞介电电泳的关键因素对不同类型的微流控细胞分离芯片进行了详细介绍，并对该技术的未来发展趋势做了展望。...

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Bibliographic Details
Published in分析化学 Vol. 43; no. 2; pp. 300 - 309
Main Author 陈礼 郑小林 胡宁 杨军 罗洪艳 姜帆 廖彦剑
Format Journal Article
LanguageChinese
Published 重庆大学生物工程学院，生物流变科学与技术教育部重点实验室，视觉损伤与再生修复重庆市重点实验室，重庆400030 2015
Subjects
介电电泳
微流控芯片
电极
细胞分离
评述
Electrodes
微流控芯片
电极
细胞分离
Microfluidic chip
Cell separation
Review
Dielectrophoresis
评述
介电电泳
Online AccessGet full text
ISSN0253-3820
DOI10.11895/j.issn.0253-3820.140793

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Summary:细胞分离技术是细胞分选和细胞种群纯化的重要手段，在生物、医学、农业、环境等许多领域都有重要的应用，是当前生化分析领域的国际研究热点。本文介绍了基于介电电泳的微流控细胞分离芯片的研究现状，阐述了介电电泳的工作原理，并依据细胞尺寸、电极形状、外加信号方式等影响细胞介电电泳的关键因素对不同类型的微流控细胞分离芯片进行了详细介绍，并对该技术的未来发展趋势做了展望。
Bibliography:Dielectrophoresis;Cell separation;Microfluidic chip;Electrodes;Review
CHEN Li, ZHENG Xiao-Lin, HU Ning, YANG Jun, LUO Hong-Yan, JIANG Fan, LIAO Yan-Jian （Key Laboratory of Biorheological Science and Technology, （Chongqing University）, Ministry of Education, and Key lab of Visual Damage and Regeneration ＆ Restoration of Chongqing, Bioengineering College, Chongqing University, Chongqing 400030, China）
22-1125/O6
Cell separation technology is an important means for cell sorting and cell-population purification. It is the current international research hot spot in biochemical analysis which has very important applications in many fields such as biology, medicine, agriculture and environment. This review introduces the development status of cell separation using microfluidic chip based on dielectrophoresis. It expounds the working principle of dielectrophoresis and the key factors such as cell size, electrode shape and signals that impacts the dielectrophoresis of cell separation on different types of microfluidic ch
ISSN:0253-3820
DOI:10.11895/j.issn.0253-3820.140793