Not Just For Men

• Published in: Survey of ophthalmology Vol. 56; no. 2; pp. 173 - 177
• Main Authors: Prat, Nicolás Molina, Sánchez-Dalmau, Bernardo F., Foroozan, Rod
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.03.2011; Elsevier
• Subjects: acute visual loss; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Blindness - etiology; Emergency and intensive care: renal failure. Dialysis management; Fatal Outcome; Female; hemodialysis; Humans; Hypertension - complications; Hypertension, Pulmonary - complications; Hypertension, Pulmonary - drug therapy; hypotension; Intensive care medicine; ischemic optic neuropathy; Kidney Failure, Chronic - complications; Kidney Failure, Chronic - therapy; Medical sciences; Middle Aged; Miscellaneous; NAION; Ophthalmology; Optic Neuropathy, Ischemic - diagnosis; Optic Neuropathy, Ischemic - etiology; Phosphodiesterase 5 Inhibitors - adverse effects; Phosphodiesterase 5 Inhibitors - therapeutic use; Piperazines - adverse effects; Piperazines - therapeutic use; Pneumology; pulmonary hypertension; Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases; Purines - adverse effects; Purines - therapeutic use; Renal Dialysis; Risk Factors; sepsis; sildenafil; Sildenafil Citrate; Sulfones - adverse effects; Sulfones - therapeutic use; Vision disorders; Visual Acuity; hypotension; acute visual loss; pulmonary hypertension; hemodialysis; ischemic optic neuropathy; NAION; sildenafil; sepsis; Vasodilator agent; Optic neuropathy; 3',5'-Cyclic-GMP phosphodiesterase; Hemodialysis; Vision disorder; Cardiovascular disease; Esterases; Phosphoric diester hydrolases; Sepsis syndrome; Extrarenal dialysis; Ischemia; Ophthalmology; Human; Enzyme; Respiratory disease; Acute; Enzyme inhibitor; Bacteremia; Pulmonary hypertension; Infection; Phosphodiesterase inhibitor; Phosphodiesterase 5 inhibitor; Eye disease; Visual impairment; Blindness; Bacteriosis; Hydrolases; Sildenafil
• ISSN: 0039-6257; 1879-3304; 1879-3304
• DOI: 10.1016/j.survophthal.2010.06.001

A 63-year-old woman developed consecutive visual loss in the presence of chronic renal failure on hemodyalisis, arterial hypertension, and pulmonary hypertension treated with sildenafil. Temporal artery biopsy was negative for giant cell arteritis. Bilateral, consecutive non-arteritic ischemic optic neuropathy was diagnosed. The implications and potential risk of sildenafil use in women are discussed.