微流控芯片在心肌标志物检测中的研究进展
心肌损伤标志物是急性心肌梗死、慢性心力衰竭和动脉粥样硬化等心血管疾病的重要检测指标之一。对心肌标志物的监测可直接影响心血管疾病患者的临床诊断、治疗方案选择和预后判断。微流控芯片以其微型化、高通量、集成化及低消耗等特点,为心肌标志物快速检测提供了一种潜在平台。本文主要介绍了微流控芯片技术在心肌标志物检测方面的研究进展,并对其发展前景予以展望。...
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| Published in | 分析化学 Vol. 43; no. 10; pp. 1490 - 1498 |
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| Main Author | |
| Format | Journal Article |
| Language | Chinese |
| Published |
中国科学院大连化学物理研究所,大连,116023
2015
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| Subjects | |
| Online Access | Get full text |
| ISSN | 0253-3820 |
| DOI | 10.11895/j.issn.0253-3820.150440 |
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| Abstract | 心肌损伤标志物是急性心肌梗死、慢性心力衰竭和动脉粥样硬化等心血管疾病的重要检测指标之一。对心肌标志物的监测可直接影响心血管疾病患者的临床诊断、治疗方案选择和预后判断。微流控芯片以其微型化、高通量、集成化及低消耗等特点,为心肌标志物快速检测提供了一种潜在平台。本文主要介绍了微流控芯片技术在心肌标志物检测方面的研究进展,并对其发展前景予以展望。 |
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| AbstractList | 心肌损伤标志物是急性心肌梗死、慢性心力衰竭和动脉粥样硬化等心血管疾病的重要检测指标之一。对心肌标志物的监测可直接影响心血管疾病患者的临床诊断、治疗方案选择和预后判断。微流控芯片以其微型化、高通量、集成化及低消耗等特点,为心肌标志物快速检测提供了一种潜在平台。本文主要介绍了微流控芯片技术在心肌标志物检测方面的研究进展,并对其发展前景予以展望。 |
| Author | 苏文涛 冯可 秦建华 |
| AuthorAffiliation | 中国科学院大连化学物理研究所,大连116023 |
| AuthorAffiliation_xml | – name: 中国科学院大连化学物理研究所,大连,116023 |
| Author_FL | QIN Jian-Hua FENG Ke SU Wen-Tao |
| Author_FL_xml | – sequence: 1 fullname: SU Wen-Tao – sequence: 2 fullname: FENG Ke – sequence: 3 fullname: QIN Jian-Hua |
| Author_xml | – sequence: 1 fullname: 苏文涛 冯可 秦建华 |
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| DOI | 10.11895/j.issn.0253-3820.150440 |
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| DocumentTitleAlternate | Progress of Microfluidics-based Immunoassays in Detection of Cardiac Markers |
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| EndPage | 1498 |
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| Keywords | 微流控芯片 免疫分析 Cardiac markers 检测方式 心肌标志物 Microfluidic chip 即时诊断 Detection mode 综述 Review Point-of-care-test Immunoassays |
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| Notes | Microfluidic chip; Immunoassays; Cardiac markers; Detection mode; Point-of-care-test; Review SU Wen-Tao, FENG Ke, QIN Jian-Hua （ Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China） 22-1125/O6 Cardiac marker is an important diagnostic index for the diagnosis of acute myocardial infarction,chronic cardiac failure or atherosclerosis. Effective monitoring of the cardiac markers can directly affect the clinical diagnosis,risk stratification,treatment options and prognosis of the patients with cardiovascular disease. The microfluidic immunoassay chip offers a potential platform for the rapid detection of cardiac markers with several remarkable characteristics,including low sample consumption,portable,high throughput and integration. In this review,we gave an overview of the recent progress of the microfluidic-based bioassays in the detection of cardiac markers. The prospects for the applications of microfluidic chip in this area were discussed as well. |
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| PublicationTitle | 分析化学 |
| PublicationTitleAlternate | Chinese Journal of Analytical Chemistry |
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| PublicationYear | 2015 |
| Publisher | 中国科学院大连化学物理研究所,大连,116023 |
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| Snippet | 心肌损伤标志物是急性心肌梗死、慢性心力衰竭和动脉粥样硬化等心血管疾病的重要检测指标之一。对心肌标志物的监测可直接影响心血管疾病患者的临床诊断、治疗方案选择和预后判... 心肌损伤标志物是急性心肌梗死、慢性心力衰竭和动脉粥样硬化等心血管疾病的重要检测指标之一.对心肌标志物的监测可直接影响心血管疾病患者的临床诊断、治疗方案选择和预后判... |
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| SubjectTerms | 免疫分析 即时诊断 微流控芯片 心肌标志物 检测方式 综述 |
| Title | 微流控芯片在心肌标志物检测中的研究进展 |
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