微流控芯片在心肌标志物检测中的研究进展

心肌损伤标志物是急性心肌梗死、慢性心力衰竭和动脉粥样硬化等心血管疾病的重要检测指标之一。对心肌标志物的监测可直接影响心血管疾病患者的临床诊断、治疗方案选择和预后判断。微流控芯片以其微型化、高通量、集成化及低消耗等特点,为心肌标志物快速检测提供了一种潜在平台。本文主要介绍了微流控芯片技术在心肌标志物检测方面的研究进展,并对其发展前景予以展望。...

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Bibliographic Details
Published in分析化学 Vol. 43; no. 10; pp. 1490 - 1498
Main Author 苏文涛 冯可 秦建华
Format Journal Article
LanguageChinese
Published 中国科学院大连化学物理研究所,大连,116023 2015
Subjects
免疫分析
即时诊断
微流控芯片
心肌标志物
检测方式
综述
微流控芯片
免疫分析
Cardiac markers
检测方式
心肌标志物
Microfluidic chip
即时诊断
Detection mode
综述
Review
Point-of-care-test
Immunoassays
Online AccessGet full text
ISSN0253-3820
DOI10.11895/j.issn.0253-3820.150440

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Summary:心肌损伤标志物是急性心肌梗死、慢性心力衰竭和动脉粥样硬化等心血管疾病的重要检测指标之一。对心肌标志物的监测可直接影响心血管疾病患者的临床诊断、治疗方案选择和预后判断。微流控芯片以其微型化、高通量、集成化及低消耗等特点,为心肌标志物快速检测提供了一种潜在平台。本文主要介绍了微流控芯片技术在心肌标志物检测方面的研究进展,并对其发展前景予以展望。
Bibliography:Microfluidic chip; Immunoassays; Cardiac markers; Detection mode; Point-of-care-test; Review
SU Wen-Tao, FENG Ke, QIN Jian-Hua （ Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China）
22-1125/O6
Cardiac marker is an important diagnostic index for the diagnosis of acute myocardial infarction,chronic cardiac failure or atherosclerosis. Effective monitoring of the cardiac markers can directly affect the clinical diagnosis,risk stratification,treatment options and prognosis of the patients with cardiovascular disease. The microfluidic immunoassay chip offers a potential platform for the rapid detection of cardiac markers with several remarkable characteristics,including low sample consumption,portable,high throughput and integration. In this review,we gave an overview of the recent progress of the microfluidic-based bioassays in the detection of cardiac markers. The prospects for the applications of microfluidic chip in this area were discussed as well.
ISSN:0253-3820
DOI:10.11895/j.issn.0253-3820.150440