Impact of Mutations in the Coreceptor Binding Site on Human Immunodeficiency Virus Type 1 Fusion, Infection, and Entry Inhibitor Sensitivity

• Published in: Journal of Virology Vol. 78; no. 10; pp. 5476 - 5485
• Main Authors: Reeves, Jacqueline D., Miamidian, John L., Biscone, Mark J., Lee, Fang-Hua, Ahmad, Navid, Pierson, Theodore C., Doms, Robert W.
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.05.2004
• Subjects: Amides - pharmacology; Anti-HIV Agents - pharmacology; Binding Sites; Biological and medical sciences; CD4 Antigens - chemistry; CD4 Antigens - metabolism; Cell Line; Enfuvirtide; Fundamental and applied biological sciences. Psychology; HIV Envelope Protein gp120 - chemistry; HIV Envelope Protein gp120 - physiology; HIV Envelope Protein gp41 - pharmacology; HIV-1 - drug effects; HIV-1 - physiology; Human immunodeficiency virus 1; Human viral diseases; Humans; Infectious diseases; Medical sciences; Membrane Fusion; Microbiology; Miscellaneous; Mutation; Peptide Fragments - pharmacology; Quaternary Ammonium Compounds - pharmacology; Receptors, CCR5 - chemistry; Receptors, CCR5 - metabolism; Structure-Activity Relationship; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; Virology; Immunopathology; Microbiology; HIV-1 virus; Retroviridae; AIDS; Binding site; Immune deficiency; Lentivirus; Virology; Infection; Virus; Sensitivity; Viral disease; Inhibitor; Human immunodeficiency virus; Mutation
• ISSN: 0022-538X; 1098-5514
• DOI: 10.1128/JVI.78.10.5476-5485.2004

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