Morphea: Evidence-based recommendations for treatment

• Published in: Indian journal of dermatology, venereology, and leprology Vol. 78; no. 2; pp. 135 - 141
• Main Author: Fett, Nicole
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer India Pvt. Ltd 01.03.2012; Medknow Publications and Media Pvt. Ltd; Scientific Scholar
• Subjects: Algorithms; Care and treatment; Clinical trials; Deformities; Dermatology - standards; Evidence-based medicine; Evidence-Based Medicine - methods; Evidence-Based Medicine - standards; Health aspects; Humans; Immunosuppressive Agents - therapeutic use; Interferon; Light therapy; Photodynamic therapy; Randomized Controlled Trials as Topic; Scleroderma (Disease); Scleroderma, Localized - drug therapy; Skin; Systemic scleroderma; India; Evidenced-based therapy; morphea treatment recommendations; morphea; localized scleroderma
• ISSN: 0378-6323; 0973-3922; 0973-3922; 1998-3611
• DOI: 10.4103/0378-6323.93628

Morphea is a rare fibrosing disorder of the skin. Evidence-based treatment strategies in morphea are lacking. This review summarizes the available data on morphea treatment and provides therapeutic strategies based on morphea subtypes. The Cochrane Library, Medline and Embase from inception until May of 2011 were searched using the key words "morphea" and "morphea treatment." Reference lists of the resultant articles, as well as relevant reviews, were also searched. This review focuses on randomized controlled trials, prospective interventional trials without controls and retrospective reviews with greater than five subjects.