Auditory dysfunction associated with solvent exposure

• Published in: BMC public health Vol. 13; no. 1; p. 39
• Main Authors: Fuente, Adrian, McPherson, Bradley, Hickson, Louise
• Format: Journal Article
• Language: English
• Published: London BioMed Central 16.01.2013; BMC
• Subjects: Adult; Age; Assessment; Audiometry - methods; Biostatistics; Cross-Sectional Studies; Emissions; Environmental Health; Epidemiology; Female; Hearing loss; Hearing Loss - chemically induced; Human subjects; Humans; Male; Medicine; Medicine & Public Health; Middle Aged; Noise; Occupational Diseases - chemically induced; Occupational exposure; Occupational Exposure - adverse effects; Occupational safety; Public Health; Research Article; Secondary education; Side effects; Solvents; Solvents - toxicity; Studies; Temporal resolution; Vaccine; Young Adult; Solvents; Temporal resolution; Assessment; Hearing loss
• ISSN: 1471-2458; 1471-2458
• DOI: 10.1186/1471-2458-13-39

Background A number of studies have demonstrated that solvents may induce auditory dysfunction. However, there is still little knowledge regarding the main signs and symptoms of solvent-induced hearing loss (SIHL). The aim of this research was to investigate the association between solvent exposure and adverse effects on peripheral and central auditory functioning with a comprehensive audiological test battery. Methods Seventy-two solvent-exposed workers and 72 non-exposed workers were selected to participate in the study. The test battery comprised pure-tone audiometry (PTA), transient evoked otoacoustic emissions (TEOAE), Random Gap Detection (RGD) and Hearing-in-Noise test (HINT). Results Solvent-exposed subjects presented with poorer mean test results than non-exposed subjects. A bivariate and multivariate linear regression model analysis was performed. One model for each auditory outcome (PTA, TEOAE, RGD and HINT) was independently constructed. For all of the models solvent exposure was significantly associated with the auditory outcome. Age also appeared significantly associated with some auditory outcomes. Conclusions This study provides further evidence of the possible adverse effect of solvents on the peripheral and central auditory functioning. A discussion of these effects and the utility of selected hearing tests to assess SIHL is addressed.