孕激素受体靶向的放射性药物研究进展

分子显像技术主要有核医学显像技术、磁共振技术、光学显像技术、超声技术等。相比其他的显像技术,核医学显像技术能够显示代谢、功能和形态学信息,具有灵敏度高和可定量等优点,可在分子水平更早的发现病变。本文从单光子和正电子类显像剂的角度综述了近年来孕激素受体靶向的放射性药物研究进展及其用于诊断孕激素受体阳性乳腺癌的研究。...

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Bibliographic Details
Published in同位素 Vol. 30; no. 1; pp. 63 - 70
Main Author 吴晓伟 张现忠
Format Journal Article
LanguageChinese
Published 厦门大学公共卫生学院分子影像暨转化医学研究中心分子疫苗学和分子诊断学国家重点实验室,厦门361102 2017
山东省泰安市中心医院核医学科,泰安271000%厦门大学公共卫生学院分子影像暨转化医学研究中心分子疫苗学和分子诊断学国家重点实验室,厦门,361102
Subjects
乳腺癌
单光子
孕激素受体
显像剂
正电子
positron
imaging agent
乳腺癌
孕激素受体
single photon
显像剂
breast cancer
progesterone receptor
单光子
正电子
Online AccessGet full text
ISSN1000-7512
DOI10.7538/tws.2017.30.01.0063

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Summary:分子显像技术主要有核医学显像技术、磁共振技术、光学显像技术、超声技术等。相比其他的显像技术,核医学显像技术能够显示代谢、功能和形态学信息,具有灵敏度高和可定量等优点,可在分子水平更早的发现病变。本文从单光子和正电子类显像剂的角度综述了近年来孕激素受体靶向的放射性药物研究进展及其用于诊断孕激素受体阳性乳腺癌的研究。
Bibliography:11-2566/TL
WU Xiao-wei1,2,ZHANG Xian-zhong1 （1.Center for Molecular Imaging and Translational Medicine, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen 361102, China;2.Nuclear Medicine Department, Taian City Central Hospital, Taian 271000, China ）
breast cancer ; progesterone receptor ; single photon ;positron ; imaging agent
Presently, several molecular imaging techniques including nuclear medicine imaging, magnetic resonance imaging, optical imaging and ultrasonic technology have been extensively used in clinic. Compared with other imaging techniques, nuclear medical imaging can not only display the metabolic, functional and morphological information of living subject, but also has the advantages of high sensitivity, quantitative research, and detecting lesions at earlier time. In this review, the recent progress of radiopharmaceuticals in the diagnosis of breast cancer by targeting to progesterone receptor was reviewed from the aspect
ISSN:1000-7512
DOI:10.7538/tws.2017.30.01.0063