A Systematic Comparison of Motion Artifact Correction Techniques for Functional Near-Infrared Spectroscopy

• Published in: Frontiers in neuroscience Vol. 6; p. 147
• Main Authors: Cooper, Robert J., Selb, Juliette, Gagnon, Louis, Phillip, Dorte, Schytz, Henrik W., Iversen, Helle K., Ashina, Messoud, Boas, David A.
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Research Foundation 01.01.2012; Frontiers Media S.A
• Subjects: functional near-infrared spectroscopy; Health sciences; hemodynamic response; Hemoglobin; I.R. radiation; Infrared spectroscopy; motion artifact; near-infrared spectroscopy; Neuroscience; NIRS; Noise; Physiology; Principal components analysis; Scalp; Sensors; Signal processing; Spectrum analysis; Wavelet transforms; Denmark; United States > US; Massachusetts; NIRS; near-infrared spectroscopy; hemodynamic response; functional near-infrared spectroscopy; motion artifact
• ISSN: 1662-4548; 1662-453X; 1662-4548; 1662-453X
• DOI: 10.3389/fnins.2012.00147

Near-infrared spectroscopy (NIRS) is susceptible to signal artifacts caused by relative motion between NIRS optical fibers and the scalp. These artifacts can be very damaging to the utility of functional NIRS, particularly in challenging subject groups where motion can be unavoidable. A number of approaches to the removal of motion artifacts from NIRS data have been suggested. In this paper we systematically compare the utility of a variety of published NIRS motion correction techniques using a simulated functional activation signal added to 20 real NIRS datasets which contain motion artifacts. Principle component analysis, spline interpolation, wavelet analysis, and Kalman filtering approaches are compared to one another and to standard approaches using the accuracy of the recovered, simulated hemodynamic response function (HRF). Each of the four motion correction techniques we tested yields a significant reduction in the mean-squared error (MSE) and significant increase in the contrast-to-noise ratio (CNR) of the recovered HRF when compared to no correction and compared to a process of rejecting motion-contaminated trials. Spline interpolation produces the largest average reduction in MSE (55%) while wavelet analysis produces the highest average increase in CNR (39%). On the basis of this analysis, we recommend the routine application of motion correction techniques (particularly spline interpolation or wavelet analysis) to minimize the impact of motion artifacts on functional NIRS data.