Patch-based super-resolution of arterial spin labeling magnetic resonance images

• Published in: NeuroImage (Orlando, Fla.) Vol. 189; pp. 85 - 94
• Main Authors: Meurée, Cédric, Maurel, Pierre, Ferré, Jean-Christophe, Barillot, Christian
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2019; Elsevier Limited; Elsevier
• Subjects: Adult; Algorithms; Arterial spin labeling; Bioengineering; Blood flow; Brain - diagnostic imaging; Brain cancer; Brain Neoplasms - diagnostic imaging; Brain tumors; Cerebral blood flow; Computer Simulation; Denoising; Female; Humans; Image Processing, Computer-Assisted - methods; Life Sciences; Magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Methods; MRI; Neuroimaging; Neuroimaging - methods; Noise; Partial volume effects; Perfusion; Spin labeling; Spin Labels; Standard deviation; Super-resolution; Super-resolution; MRI; Arterial spin labeling; Partial volume effects; Denoising; Super-Resolution; Partial Volume Effects; Arterial Spin Labeling
• ISSN: 1053-8119; 1095-9572; 1095-9572
• DOI: 10.1016/j.neuroimage.2019.01.004

Arterial spin labeling is a magnetic resonance perfusion imaging technique that, while providing results comparable to methods currently considered as more standard concerning the quantification of the cerebral blood flow, is subject to limitations related to its low signal-to-noise ratio and low resolution. In this work, we investigate the relevance of using a non-local patch-based super-resolution method driven by a high resolution structural image to increase the level of details in arterial spin labeling images. This method is evaluated by comparison with other image dimension increasing techniques on a simulated dataset, on images of healthy subjects and on images of subjects scanned for brain tumors, who had a dynamic susceptibility contrast acquisition. The influence of an increase of ASL images resolution on partial volume effects is also investigated in this work. •Super-resolution for arterial spin labeling magnetic resonance images is validated.•Validation on simulations, healthy subjects and dynamic susceptibility contrast.•High resolution reconstructed images are closer to reference images.•Super-resolution reduces partial volume effects in cerebral blood flow images.