Risk factors of video urodynamics and bladder management for long-term complications in patients with chronic spinal cord injury

• Published in: Scientific reports Vol. 14; no. 1; pp. 12632 - 6
• Main Authors: Chen, Yu-Chen, Kuo, Hann-Chorng
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 02.06.2024; Nature Publishing Group; Nature Portfolio
• Subjects: 692/4025; 692/499; Adult; Aged; Bladder; Chronic Disease; Complications; Female; Health risks; Humanities and Social Sciences; Humans; Hydronephrosis; Kidney diseases; Male; Middle Aged; multidisciplinary; Neurogenic bladder; Risk Factors; Risk reduction; Science; Science (multidisciplinary); Self-catheterization; Sphincter; Spinal cord injuries; Spinal Cord Injuries - complications; Spinal Cord Injuries - physiopathology; Urinary Bladder - physiopathology; Urinary catheterization; Urinary tract; Urinary Tract Infections - etiology; Urodynamics; Urodynamics; Spinal cord injuries; Urinary catheterization; Self-catheterization; Complications; Neurogenic bladder
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-024-63441-w

This study explores 15-year urological complications in chronic spinal cord injury (SCI) patients and investigates the predictive factors from video-urodynamic study (VUDS) and bladder management. Analyzing 864 SCI patients with a mean 15.6-year follow-up, we assessed complications and utilized multivariate logistic regression for risk evaluation. VUDS factors such as autonomic dysreflexia, detrusor sphincter dyssynergia, vesicourethral reflux (VUR), contracted bladder, and high voiding detrusor pressure significantly increased the likelihood of recurrent urinary tract infections (rUTI). Low bladder compliance, VUR, and contracted bladder notably raised the risk of hydronephrosis, while contracted bladder and detrusor overactivity with detrusor underactivity heightened chronic kidney disease risk. Volitional voiding reduced rUTI and VUR risk, whereas Valsalva maneuver-assisted voiding increased hydronephrosis risk. In conclusion, a contracted bladder identified in VUDS is associated with long-term urological complications in SCI, we propose that patients already experiencing a contracted bladder should prioritize volitional voiding as their preferred bladder management strategy to minimize the risk of additional complications such as rUTI and VUR. These findings unveil previously unexplored aspects in research, emphasizing the need for proactive management strategies in this patient population.