Painting with light-powered bacteria

• Published in: Nature communications Vol. 9; no. 1; pp. 768 - 7
• Main Authors: Arlt, Jochen, Martinez, Vincent A., Dawson, Angela, Pilizota, Teuta, Poon, Wilson C. K.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 22.02.2018; Nature Publishing Group; Nature Portfolio
• Subjects: 639/301/923/966; 639/766/530/2804; Bacteria; Biology; E coli; Escherichia coli - chemistry; Escherichia coli - genetics; Escherichia coli - physiology; Escherichia coli - radiation effects; Fabrication; Humanities and Social Sciences; Kinetics; Light; Light intensity; Luminous intensity; Motility; multidisciplinary; Phase transitions; Physics; Precision medicine; Science; Science (multidisciplinary); Self-assembly; Sharpness; Swimming
• ISSN: 2041-1723; 2041-1723
• DOI: 10.1038/s41467-018-03161-8

Self-assembly is a promising route for micro- and nano-fabrication with potential to revolutionise many areas of technology, including personalised medicine. Here we demonstrate that external control of the swimming speed of microswimmers can be used to self assemble reconfigurable designer structures in situ. We implement such ‘smart templated active self assembly’ in a fluid environment by using spatially patterned light fields to control photon-powered strains of motile Escherichia coli bacteria. The physics and biology governing the sharpness and formation speed of patterns is investigated using a bespoke strain designed to respond quickly to changes in light intensity. Our protocol provides a distinct paradigm for self-assembly of structures on the 10 μm to mm scale. The ability to generate microscale patterns and control microswimmers may be useful for engineering smart materials. Here Arlt et al. use genetically modified bacteria with fast response to changes in light intensity to produce light-induced patterns.