Evaluation of the Effect of Jawarish Amla Concoction on Controlling Stress in Women Candidate Intracytoplasmic Sperm Injection or In Vitro Fertilization: A Randomized Clinical Trial
Background: Infertility diagnostic investigations and treatment through assisted reproductive technology (ART) predispose infertile women to stress, while stress itself can severely affect the results of infertility treatment. This research aimed to investigate the effect of Jawarish Amla Concoction...
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| Published in | Advanced biomedical research Vol. 14; no. 1; p. 84 |
|---|---|
| Main Authors | , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
India
Wolters Kluwer - Medknow
01.08.2025
Medknow Publications and Media Pvt. Ltd Medknow Publications & Media Pvt. Ltd Wolters Kluwer Medknow Publications |
| Edition | 2 |
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| Online Access | Get full text |
| ISSN | 2277-9175 2277-9175 |
| DOI | 10.4103/abr.abr_249_24 |
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| Abstract | Background:
Infertility diagnostic investigations and treatment through assisted reproductive technology (ART) predispose infertile women to stress, while stress itself can severely affect the results of infertility treatment. This research aimed to investigate the effect of Jawarish Amla Concoction on controlling stress in female candidate intracytoplasmic sperm injection (ICSI) or in vitro fertilization (IVF).
Materials and Methods:
This randomized clinical trial was conducted between December 2022 and June 2023 at Shahid Akbarabadi Hospital, affiliated with the Iran University of Medical Sciences (IRCT20230411057883N1). A sample of 100 infertile female candidates for ICSI/IVF was randomly divided into two groups. Patients in the intervention group received one tablespoon of the Jawarish Amla Concoction (Phyllanthus emblica, Rosa damascene, and honey). The control group was only followed up on without any intervention. The stress level of the patients was measured based on Newton's Fertility Problem Inventory (FPI) at the beginning and end of the study, and its changes were compared in both groups.
Results:
Ninety women completed the study, and their data were analyzed. The mean FPI score in the intervention group was 160.76 ± 28.2 before the intervention and 153.39 ± 28.5 after the intervention, while it was respectively 141.07 ± 25.58 and 142.8 ± 31.05 in the control group. After four weeks, the percentage of changes in the FPI score was 16.67 ± 3.32% in the intervention group and 11.28 ± 1.18% in the control group (P = 0.045). No complications were observed.
Conclusion:
Consuming the Jawarish Amla Concoction for four weeks significantly reduced stress in female candidates for ICSI/IVF. |
|---|---|
| AbstractList | Background: Infertility diagnostic investigations and treatment through assisted reproductive technology (ART) predispose infertile women to stress, while stress itself can severely affect the results of infertility treatment. This research aimed to investigate the effect of Jawarish Amla Concoction on controlling stress in female candidate intracytoplasmic sperm injection (ICSI) or in vitro fertilization (IVF). Materials and Methods: This randomized clinical trial was conducted between December 2022 and June 2023 at Shahid Akbarabadi Hospital, affiliated with the Iran University of Medical Sciences (IRCT20230411057883N1). A sample of 100 infertile female candidates for ICSI/IVF was randomly divided into two groups. Patients in the intervention group received one tablespoon of the Jawarish Amla Concoction (Phyllanthus emblica, Rosa damascene, and honey). The control group was only followed up on without any intervention. The stress level of the patients was measured based on Newton's Fertility Problem Inventory (FPI) at the beginning and end of the study, and its changes were compared in both groups. Results: Ninety women completed the study, and their data were analyzed. The mean FPI score in the intervention group was 160.76 ± 28.2 before the intervention and 153.39 ± 28.5 after the intervention, while it was respectively 141.07 ± 25.58 and 142.8 ± 31.05 in the control group. After four weeks, the percentage of changes in the FPI score was 16.67 ± 3.32% in the intervention group and 11.28 ± 1.18% in the control group (P = 0.045). No complications were observed. Conclusion: Consuming the Jawarish Amla Concoction for four weeks significantly reduced stress in female candidates for ICSI/IVF. Keywords: Infertility, mental health, Persian medicine, phyllanthus emblica, stress Infertility diagnostic investigations and treatment through assisted reproductive technology (ART) predispose infertile women to stress, while stress itself can severely affect the results of infertility treatment. This research aimed to investigate the effect of Jawarish Amla Concoction on controlling stress in female candidate intracytoplasmic sperm injection (ICSI) or in vitro fertilization (IVF).BackgroundInfertility diagnostic investigations and treatment through assisted reproductive technology (ART) predispose infertile women to stress, while stress itself can severely affect the results of infertility treatment. This research aimed to investigate the effect of Jawarish Amla Concoction on controlling stress in female candidate intracytoplasmic sperm injection (ICSI) or in vitro fertilization (IVF).This randomized clinical trial was conducted between December 2022 and June 2023 at Shahid Akbarabadi Hospital, affiliated with the Iran University of Medical Sciences (IRCT20230411057883N1). A sample of 100 infertile female candidates for ICSI/IVF was randomly divided into two groups. Patients in the intervention group received one tablespoon of the Jawarish Amla Concoction (Phyllanthus emblica, Rosa damascene, and honey). The control group was only followed up on without any intervention. The stress level of the patients was measured based on Newton's Fertility Problem Inventory (FPI) at the beginning and end of the study, and its changes were compared in both groups.Materials and MethodsThis randomized clinical trial was conducted between December 2022 and June 2023 at Shahid Akbarabadi Hospital, affiliated with the Iran University of Medical Sciences (IRCT20230411057883N1). A sample of 100 infertile female candidates for ICSI/IVF was randomly divided into two groups. Patients in the intervention group received one tablespoon of the Jawarish Amla Concoction (Phyllanthus emblica, Rosa damascene, and honey). The control group was only followed up on without any intervention. The stress level of the patients was measured based on Newton's Fertility Problem Inventory (FPI) at the beginning and end of the study, and its changes were compared in both groups.Ninety women completed the study, and their data were analyzed. The mean FPI score in the intervention group was 160.76 ± 28.2 before the intervention and 153.39 ± 28.5 after the intervention, while it was respectively 141.07 ± 25.58 and 142.8 ± 31.05 in the control group. After four weeks, the percentage of changes in the FPI score was 16.67 ± 3.32% in the intervention group and 11.28 ± 1.18% in the control group (P = 0.045). No complications were observed.ResultsNinety women completed the study, and their data were analyzed. The mean FPI score in the intervention group was 160.76 ± 28.2 before the intervention and 153.39 ± 28.5 after the intervention, while it was respectively 141.07 ± 25.58 and 142.8 ± 31.05 in the control group. After four weeks, the percentage of changes in the FPI score was 16.67 ± 3.32% in the intervention group and 11.28 ± 1.18% in the control group (P = 0.045). No complications were observed.Consuming the Jawarish Amla Concoction for four weeks significantly reduced stress in female candidates for ICSI/IVF.ConclusionConsuming the Jawarish Amla Concoction for four weeks significantly reduced stress in female candidates for ICSI/IVF. Infertility diagnostic investigations and treatment through assisted reproductive technology (ART) predispose infertile women to stress, while stress itself can severely affect the results of infertility treatment. This research aimed to investigate the effect of on controlling stress in female candidate intracytoplasmic sperm injection (ICSI) or fertilization (IVF). This randomized clinical trial was conducted between December 2022 and June 2023 at Shahid Akbarabadi Hospital, affiliated with the Iran University of Medical Sciences (IRCT20230411057883N1). A sample of 100 infertile female candidates for ICSI/IVF was randomly divided into two groups. Patients in the intervention group received one tablespoon of the ( , and honey). The control group was only followed up on without any intervention. The stress level of the patients was measured based on Newton's Fertility Problem Inventory (FPI) at the beginning and end of the study, and its changes were compared in both groups. Ninety women completed the study, and their data were analyzed. The mean FPI score in the intervention group was 160.76 ± 28.2 before the intervention and 153.39 ± 28.5 after the intervention, while it was respectively 141.07 ± 25.58 and 142.8 ± 31.05 in the control group. After four weeks, the percentage of changes in the FPI score was 16.67 ± 3.32% in the intervention group and 11.28 ± 1.18% in the control group ( = 0.045). No complications were observed. Consuming the for four weeks significantly reduced stress in female candidates for ICSI/IVF. Infertility diagnostic investigations and treatment through assisted reproductive technology (ART) predispose infertile women to stress, while stress itself can severely affect the results of infertility treatment. This research aimed to investigate the effect of Jawarish Amla Concoction on controlling stress in female candidate intracytoplasmic sperm injection (ICSI) or in vitro fertilization (IVF). This randomized clinical trial was conducted between December 2022 and June 2023 at Shahid Akbarabadi Hospital, affiliated with the Iran University of Medical Sciences (IRCT20230411057883N1). A sample of 100 infertile female candidates for ICSI/IVF was randomly divided into two groups. Patients in the intervention group received one tablespoon of the Jawarish Amla Concoction (Phyllanthus emblica, Rosa damascene, and honey). The control group was only followed up on without any intervention. The stress level of the patients was measured based on Newton's Fertility Problem Inventory (FPI) at the beginning and end of the study, and its changes were compared in both groups. Ninety women completed the study, and their data were analyzed. The mean FPI score in the intervention group was 160.76 ± 28.2 before the intervention and 153.39 ± 28.5 after the intervention, while it was respectively 141.07 ± 25.58 and 142.8 ± 31.05 in the control group. After four weeks, the percentage of changes in the FPI score was 16.67 ± 3.32% in the intervention group and 11.28 ± 1.18% in the control group (P = 0.045). No complications were observed. Consuming the Jawarish Amla Concoction for four weeks significantly reduced stress in female candidates for ICSI/IVF. Background:Infertility diagnostic investigations and treatment through assisted reproductive technology (ART) predispose infertile women to stress, while stress itself can severely affect the results of infertility treatment. This research aimed to investigate the effect of Jawarish Amla Concoction on controlling stress in female candidate intracytoplasmic sperm injection (ICSI) or in vitro fertilization (IVF).Materials and Methods:This randomized clinical trial was conducted between December 2022 and June 2023 at Shahid Akbarabadi Hospital, affiliated with the Iran University of Medical Sciences (IRCT20230411057883N1). A sample of 100 infertile female candidates for ICSI/IVF was randomly divided into two groups. Patients in the intervention group received one tablespoon of the Jawarish Amla Concoction (Phyllanthus emblica, Rosa damascene, and honey). The control group was only followed up on without any intervention. The stress level of the patients was measured based on Newton’s Fertility Problem Inventory (FPI) at the beginning and end of the study, and its changes were compared in both groups.Results:Ninety women completed the study, and their data were analyzed. The mean FPI score in the intervention group was 160.76 ± 28.2 before the intervention and 153.39 ± 28.5 after the intervention, while it was respectively 141.07 ± 25.58 and 142.8 ± 31.05 in the control group. After four weeks, the percentage of changes in the FPI score was 16.67 ± 3.32% in the intervention group and 11.28 ± 1.18% in the control group (P = 0.045). No complications were observed.Conclusion:Consuming the Jawarish Amla Concoction for four weeks significantly reduced stress in female candidates for ICSI/IVF. Background: Infertility diagnostic investigations and treatment through assisted reproductive technology (ART) predispose infertile women to stress, while stress itself can severely affect the results of infertility treatment. This research aimed to investigate the effect of Jawarish Amla Concoction on controlling stress in female candidate intracytoplasmic sperm injection (ICSI) or in vitro fertilization (IVF). Materials and Methods: This randomized clinical trial was conducted between December 2022 and June 2023 at Shahid Akbarabadi Hospital, affiliated with the Iran University of Medical Sciences (IRCT20230411057883N1). A sample of 100 infertile female candidates for ICSI/IVF was randomly divided into two groups. Patients in the intervention group received one tablespoon of the Jawarish Amla Concoction (Phyllanthus emblica, Rosa damascene, and honey). The control group was only followed up on without any intervention. The stress level of the patients was measured based on Newton's Fertility Problem Inventory (FPI) at the beginning and end of the study, and its changes were compared in both groups. Results: Ninety women completed the study, and their data were analyzed. The mean FPI score in the intervention group was 160.76 ± 28.2 before the intervention and 153.39 ± 28.5 after the intervention, while it was respectively 141.07 ± 25.58 and 142.8 ± 31.05 in the control group. After four weeks, the percentage of changes in the FPI score was 16.67 ± 3.32% in the intervention group and 11.28 ± 1.18% in the control group (P = 0.045). No complications were observed. Conclusion: Consuming the Jawarish Amla Concoction for four weeks significantly reduced stress in female candidates for ICSI/IVF. |
| Audience | Academic |
| Author | Kadkhodaei, Samira Hashem-Dabaghian, Fataneh Bashiri, Maryam Mahroozade, Somayye Isakhani, Marzieh Taghavi Shirazi, Maryam Yousefsani, BahareSadat Javedani Masroor, Mojgan Bioos, Soodabe |
| Author_xml | – sequence: 1 givenname: Marzieh surname: Isakhani fullname: Isakhani, Marzieh – sequence: 2 givenname: BahareSadat surname: Yousefsani fullname: Yousefsani, BahareSadat – sequence: 3 givenname: Mojgan surname: Javedani Masroor fullname: Javedani Masroor, Mojgan – sequence: 4 givenname: Maryam surname: Bashiri fullname: Bashiri, Maryam – sequence: 5 givenname: Fataneh surname: Hashem-Dabaghian fullname: Hashem-Dabaghian, Fataneh – sequence: 6 givenname: Soodabe surname: Bioos fullname: Bioos, Soodabe – sequence: 7 givenname: Maryam surname: Taghavi Shirazi fullname: Taghavi Shirazi, Maryam – sequence: 8 givenname: Samira surname: Kadkhodaei fullname: Kadkhodaei, Samira – sequence: 9 givenname: Somayye surname: Mahroozade fullname: Mahroozade, Somayye |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/40958918$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1111/j.1755-5949.2011.00256.x 10.1093/hropen/hoaa059 10.1111/aji.12832 10.3390/molecules26113322 10.1016/j.mefs.2016.07.002 10.1371/journal.pone.0063743 10.1016/j.ctim.2017.08.014 10.1016/j.jff.2023.105884 10.2174/1871527319666200117105133 10.1016/j.bionut.2013.12.011 10.1039/C9FO00767A 10.1007/s00737-018-0911-5 10.4103/0974-8520.92544 10.1093/humrep/des383 10.1080/10253890.2019.1584181 10.1016/j.ijgo.2008.12.013 10.1016/S0015-0282(99)00164-8 10.1016/j.ajog.2016.01.170 10.3390/molecules26030649 10.1186/s12905-019-0856-5 10.1111/jphp.13185 10.1007/s00404-024-07444-y 10.1080/13651501.2021.1872647 10.1016/j.fertnstert.2016.01.036 10.1080/1028415X.2022.2063578 |
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Infertility diagnostic investigations and treatment through assisted reproductive technology (ART) predispose infertile women to stress, while... Infertility diagnostic investigations and treatment through assisted reproductive technology (ART) predispose infertile women to stress, while stress itself... Background: Infertility diagnostic investigations and treatment through assisted reproductive technology (ART) predispose infertile women to stress, while... Background:Infertility diagnostic investigations and treatment through assisted reproductive technology (ART) predispose infertile women to stress, while... |
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| Title | Evaluation of the Effect of Jawarish Amla Concoction on Controlling Stress in Women Candidate Intracytoplasmic Sperm Injection or In Vitro Fertilization: A Randomized Clinical Trial |
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