Results of 2500 office-based diagnostic hysteroscopies before IVF

• Published in: Reproductive biomedicine online Vol. 20; no. 5; pp. 689 - 693
• Main Authors: Karayalcin, Rana, Ozcan, Sarp, Moraloglu, Ozlem, Ozyer, Sebnem, Mollamahmutoglu, Leyla, Batıoglu, Sertac
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.05.2010
• Subjects: endometrial pathology; Female; Fertilization in Vitro; Humans; Hysteroscopy; in-vitro fertilization; Infertility, Female - diagnosis; Infertility, Female - physiopathology; Obstetrics and Gynecology; office-based hysteroscopy; Prospective Studies; Uterine Diseases - diagnosis; Uterine Diseases - physiopathology; endometrial pathology; in-vitro fertilization; office-based hysteroscopy
• ISSN: 1472-6483; 1472-6491; 1472-6491
• DOI: 10.1016/j.rbmo.2009.12.030

The aim of the study is to assess the diagnostic accuracy, findings and feasibility of office-based diagnostic hysteroscopy in an IVF population. A total of 2500 consecutive infertile patients were enrolled prospectively prior to IVF treatment. Diagnostic hysteroscopy was performed on each subject in an office setting in the study IVF centre. A total of 1927 patients (77.1%) had a normal uterine cavity, while the remainder of the sample ( n = 573) demonstrated endometrial pathology on hysteroscopy (22.9%). Of the patients with endometrial pathology, 192 patients had endometrial polyps (7.68%), 96 patients had submucosal fibroids (3.84%), 31 patients had polypoid endometria (1.24%), 27 patients had intrauterine adhesions (1.08%) and 73 patients had uterine septa (2.92%). Diagnostic office-based hysteroscopy is routinely performed in the IVF clinic to assess the endometrial cavity. In such an unselected population, a significant percentage of patients had evidence of uterine pathology that may have impaired the success of IVF. Safety, ease of use, high diagnostic accuracy and high patient tolerance makes office-based hysteroscopy an ideal procedure.