A case of focal nodular hyperplasia with growth progression during pregnancy

• Published in: Clinical and molecular hepatology Vol. 20; no. 4; pp. 392 - 397
• Main Authors: Kim, Min Ji, Han, Sang Young, Baek, Yang Hyun, Lee, Sung Wook, Kwon, Hee Jin
• Format: Journal Article
• Language: English
• Published: Korea (South) Korean Association for the Study of the Liver 01.12.2014; The Korean Association for the Study of the Liver; 대한간학회
• Subjects: Abdomen; Adult; alpha-Fetoproteins - analysis; Biopsy; Blood; Case Report; Contrast agents; Female; Focal nodular hyperplasia; Focal Nodular Hyperplasia - diagnosis; Focal Nodular Hyperplasia - diagnostic imaging; Hemangioma; Hemorrhage; Hepatic adenoma; Humans; Hyperplasia; Liver; Liver - diagnostic imaging; Liver - pathology; Magnetic resonance imaging; Medical history; Outpatient care facilities; Postpartum period; Pregnancy; Tomography, X-Ray Computed; Tumors; Ultrasonic imaging; Ultrasonography; 내과학; Pregnancy; Hepatic adenoma; Focal nodular hyperplasia
• ISSN: 2287-2728; 2287-285X; 2287-285X
• DOI: 10.3350/cmh.2014.20.4.392

Focal nodular hyperplasia (FNH) is the second most common benign solid tumor of the liver and is usually found in young females. In FNH, spontaneous bleeding or rupture rarely occurs and malignant transformation is unlikely. The etiology of FNH is unclear, but because of female predominance and young age at onset, it seems that female hormone has an important role for the development of FNH. Although the development and the complications of hepatocellular adenomas have been related to the use of oral contraceptives and pregnancy, the influence of oral contraceptives and pregnancy on the growth and complications of FNH is controversial. Most FNH are stable in size and rarely complicated during pregnancy. We describe here a case of FNH with growth progression during pregnancy in a 27-year-old female. Her course of pregnancy and delivery was uneventful. Two months after delivery, the size of FNH was decreased.