Effects of Aerobic Exercise vs. Resistance Training on Endothelial Function in Women with Type 2 Diabetes Mellitus

There is controversy over whether aerobic or resistance exercise is more effective for improving endothelial function in type 2 diabetes mellitus (T2DM). This study was aimed to investigate the effects of an aerobic and resistance training program on endothelial function, and the influences of glyce...

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Published inDiabetes & metabolism journal Vol. 35; no. 4; pp. 364 - 373
Main Authors Kwon, Hwi Ryun, Min, Kyung Wan, Ahn, Hee Jung, Seok, Hee Geum, Lee, Jae Hyuk, Park, Gang Seo, Han, Kyung Ah
Format Journal Article
LanguageEnglish
Published Korea (South) Korean Diabetes Association / Daehan Dangnyobyeong Hakoe 01.08.2011
Korean Diabetes Association
대한당뇨병학회
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ISSN2233-6079
2233-6087
2233-6087
DOI10.4093/dmj.2011.35.4.364

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Abstract There is controversy over whether aerobic or resistance exercise is more effective for improving endothelial function in type 2 diabetes mellitus (T2DM). This study was aimed to investigate the effects of an aerobic and resistance training program on endothelial function, and the influences of glycemic control, body weight changes, and aerobic capacity in T2DM. Total 40 overweight women with T2DM were assigned into 3 groups: an aerobic exercise group (AEG, n=13), resistance exercise group (REG, n=12), and control group (CG, n=15), and followed either brisk walking for the AEG or resistance band training for the REG, 60 minutes per day, 5 days per week for 12 weeks with monitoring daily activity using accelerometers. We assessed endothelial function by flow-mediated dilation (FMD), and aerobic capacity by oxygen uptake at anaerobic threshold (AT_VO(2)) at baseline and following training program. The mean participants' age was 57.0±6.8 years, and body mass index (BMI) was 27.0±2.3 kg/m(2). After intervention, FMD increased by 2.2±1.9% in AEG, which differed from REG and CG (P=0.002), despite of decreased body weight (BW) in both AG and RG (2.8±2.5%, P=0.002; 1.6±2.0%, P=0.017, respectively). A significant increased AT_VO(2) and decreased HbA1c were found only in AEG. In all participants, FMD was changed with the significant relations to the AT_VO(2) (r=0.348, P=0.035), but not to HbA1c levels or BW. Aerobic exercise appears to be more beneficial than resistance exercise for improving endothelial function in T2DM. In addition, aerobic capacity could be a better predictor of changes in FMD than BW and glycemic control.
AbstractList There is controversy over whether aerobic or resistance exercise is more effective for improving endothelial function in type 2 diabetes mellitus (T2DM). This study was aimed to investigate the effects of an aerobic and resistance training program on endothelial function, and the influences of glycemic control, body weight changes, and aerobic capacity in T2DM.BACKGROUNDThere is controversy over whether aerobic or resistance exercise is more effective for improving endothelial function in type 2 diabetes mellitus (T2DM). This study was aimed to investigate the effects of an aerobic and resistance training program on endothelial function, and the influences of glycemic control, body weight changes, and aerobic capacity in T2DM.Total 40 overweight women with T2DM were assigned into 3 groups: an aerobic exercise group (AEG, n=13), resistance exercise group (REG, n=12), and control group (CG, n=15), and followed either brisk walking for the AEG or resistance band training for the REG, 60 minutes per day, 5 days per week for 12 weeks with monitoring daily activity using accelerometers. We assessed endothelial function by flow-mediated dilation (FMD), and aerobic capacity by oxygen uptake at anaerobic threshold (AT_VO(2)) at baseline and following training program.METHODSTotal 40 overweight women with T2DM were assigned into 3 groups: an aerobic exercise group (AEG, n=13), resistance exercise group (REG, n=12), and control group (CG, n=15), and followed either brisk walking for the AEG or resistance band training for the REG, 60 minutes per day, 5 days per week for 12 weeks with monitoring daily activity using accelerometers. We assessed endothelial function by flow-mediated dilation (FMD), and aerobic capacity by oxygen uptake at anaerobic threshold (AT_VO(2)) at baseline and following training program.The mean participants' age was 57.0±6.8 years, and body mass index (BMI) was 27.0±2.3 kg/m(2). After intervention, FMD increased by 2.2±1.9% in AEG, which differed from REG and CG (P=0.002), despite of decreased body weight (BW) in both AG and RG (2.8±2.5%, P=0.002; 1.6±2.0%, P=0.017, respectively). A significant increased AT_VO(2) and decreased HbA1c were found only in AEG. In all participants, FMD was changed with the significant relations to the AT_VO(2) (r=0.348, P=0.035), but not to HbA1c levels or BW.RESULTSThe mean participants' age was 57.0±6.8 years, and body mass index (BMI) was 27.0±2.3 kg/m(2). After intervention, FMD increased by 2.2±1.9% in AEG, which differed from REG and CG (P=0.002), despite of decreased body weight (BW) in both AG and RG (2.8±2.5%, P=0.002; 1.6±2.0%, P=0.017, respectively). A significant increased AT_VO(2) and decreased HbA1c were found only in AEG. In all participants, FMD was changed with the significant relations to the AT_VO(2) (r=0.348, P=0.035), but not to HbA1c levels or BW.Aerobic exercise appears to be more beneficial than resistance exercise for improving endothelial function in T2DM. In addition, aerobic capacity could be a better predictor of changes in FMD than BW and glycemic control.CONCLUSIONAerobic exercise appears to be more beneficial than resistance exercise for improving endothelial function in T2DM. In addition, aerobic capacity could be a better predictor of changes in FMD than BW and glycemic control.
Background: There is controversy over whether aerobic or resistance exercise is more effective for improving endothelial function in type 2 diabetes mellitus (T2DM). This study was aimed to investigate the effects of an aerobic and resistance training program on endothelial function, and the influences of glycemic control, body weight changes, and aerobic capacity in T2DM. Methods: Total 40 overweight women with T2DM were assigned into 3 groups: an aerobic exercise group (AEG, n=13), resistance exercise group (REG, n=12), and control group (CG, n=15), and followed either brisk walking for the AEG or resistance band training for the REG, 60 minutes per day, 5 days per week for 12 weeks with monitoring daily activity using accelerometers. We assessed endothelial function by flow-mediated dilation (FMD), and aerobic capacity by oxygen uptake at anaerobic threshold (AT_VO_2) at baseline and following training program. Results: The mean participants’ age was 57.0±6.8 years, and body mass index (BMI) was 27.0±2.3 kg/m^2. After intervention, FMD increased by 2.2±1.9% in AEG, which differed from REG and CG (P=0.002), despite of decreased body weight (BW) in both AG and RG (2.8±2.5%, P=0.002; 1.6±2.0%, P=0.017, respectively). A significant increased AT_VO_2 and decreased HbA1c were found only in AEG. In all participants, FMD was changed with the significant relations to the AT_VO_2 (r=0.348, P=0.035), but not to HbA1c levels or BW. Conclusion: Aerobic exercise appears to be more beneficial than resistance exercise for improving endothelial function in T2DM. In addition, aerobic capacity could be a better predictor of changes in FMD than BW and glycemic control. KCI Citation Count: 3
Background There is controversy over whether aerobic or resistance exercise is more effective for improving endothelial function in type 2 diabetes mellitus (T2DM). This study was aimed to investigate the effects of an aerobic and resistance training program on endothelial function, and the influences of glycemic control, body weight changes, and aerobic capacity in T2DM.* Methods Total 40 overweight women with T2DM were assigned into 3 groups: an aerobic exercise group (AEG, n=13), resistance exercise group (REG, n=12), and control group (CG, n=15), and followed either brisk walking for the AEG or resistance band training for the REG, 60 minutes per day, 5 days per week for 12 weeks with monitoring daily activity using accelerometers. We assessed endothelial function by flow-mediated dilation (FMD), and aerobic capacity by oxygen uptake at anaerobic threshold (AT_VO2) at baseline and following training program.* Results The mean participants' age was 57.0±6.8 years, and body mass index (BMI) was 27.0±2.3 kg/m2. After intervention, FMD increased by 2.2±1.9% in AEG, which differed from REG and CG (P=0.002), despite of decreased body weight (BW) in both AG and RG (2.8±2.5%, P=0.002; 1.6±2.0%, P=0.017, respectively). A significant increased AT_VO2 and decreased HbA1c were found only in AEG. In all participants, FMD was changed with the significant relations to the AT_VO2 (r=0.348, P=0.035), but not to HbA1c levels or BW.* Conclusion Aerobic exercise appears to be more beneficial than resistance exercise for improving endothelial function in T2DM. In addition, aerobic capacity could be a better predictor of changes in FMD than BW and glycemic control.
There is controversy over whether aerobic or resistance exercise is more effective for improving endothelial function in type 2 diabetes mellitus (T2DM). This study was aimed to investigate the effects of an aerobic and resistance training program on endothelial function, and the influences of glycemic control, body weight changes, and aerobic capacity in T2DM. Total 40 overweight women with T2DM were assigned into 3 groups: an aerobic exercise group (AEG, n=13), resistance exercise group (REG, n=12), and control group (CG, n=15), and followed either brisk walking for the AEG or resistance band training for the REG, 60 minutes per day, 5 days per week for 12 weeks with monitoring daily activity using accelerometers. We assessed endothelial function by flow-mediated dilation (FMD), and aerobic capacity by oxygen uptake at anaerobic threshold (AT_VO(2)) at baseline and following training program. The mean participants' age was 57.0±6.8 years, and body mass index (BMI) was 27.0±2.3 kg/m(2). After intervention, FMD increased by 2.2±1.9% in AEG, which differed from REG and CG (P=0.002), despite of decreased body weight (BW) in both AG and RG (2.8±2.5%, P=0.002; 1.6±2.0%, P=0.017, respectively). A significant increased AT_VO(2) and decreased HbA1c were found only in AEG. In all participants, FMD was changed with the significant relations to the AT_VO(2) (r=0.348, P=0.035), but not to HbA1c levels or BW. Aerobic exercise appears to be more beneficial than resistance exercise for improving endothelial function in T2DM. In addition, aerobic capacity could be a better predictor of changes in FMD than BW and glycemic control.
BackgroundThere is controversy over whether aerobic or resistance exercise is more effective for improving endothelial function in type 2 diabetes mellitus (T2DM). This study was aimed to investigate the effects of an aerobic and resistance training program on endothelial function, and the influences of glycemic control, body weight changes, and aerobic capacity in T2DM.MethodsTotal 40 overweight women with T2DM were assigned into 3 groups: an aerobic exercise group (AEG, n=13), resistance exercise group (REG, n=12), and control group (CG, n=15), and followed either brisk walking for the AEG or resistance band training for the REG, 60 minutes per day, 5 days per week for 12 weeks with monitoring daily activity using accelerometers. We assessed endothelial function by flow-mediated dilation (FMD), and aerobic capacity by oxygen uptake at anaerobic threshold (AT_VO2) at baseline and following training program.ResultsThe mean participants' age was 57.0±6.8 years, and body mass index (BMI) was 27.0±2.3 kg/m2. After intervention, FMD increased by 2.2±1.9% in AEG, which differed from REG and CG (P=0.002), despite of decreased body weight (BW) in both AG and RG (2.8±2.5%, P=0.002; 1.6±2.0%, P=0.017, respectively). A significant increased AT_VO2 and decreased HbA1c were found only in AEG. In all participants, FMD was changed with the significant relations to the AT_VO2 (r=0.348, P=0.035), but not to HbA1c levels or BW.ConclusionAerobic exercise appears to be more beneficial than resistance exercise for improving endothelial function in T2DM. In addition, aerobic capacity could be a better predictor of changes in FMD than BW and glycemic control.
Author Min, Kyung Wan
Park, Gang Seo
Han, Kyung Ah
Ahn, Hee Jung
Seok, Hee Geum
Kwon, Hwi Ryun
Lee, Jae Hyuk
AuthorAffiliation 2 Department of Internal Medicine, Eulji University College of Medicine, Seoul, Korea
1 Diabetes Center, Eulji Hospital, Seoul, Korea
AuthorAffiliation_xml – name: 2 Department of Internal Medicine, Eulji University College of Medicine, Seoul, Korea
– name: 1 Diabetes Center, Eulji Hospital, Seoul, Korea
Author_xml – sequence: 1
  givenname: Hwi Ryun
  surname: Kwon
  fullname: Kwon, Hwi Ryun
  organization: Diabetes Center, Eulji Hospital, Seoul, Korea
– sequence: 2
  givenname: Kyung Wan
  surname: Min
  fullname: Min, Kyung Wan
  organization: Department of Internal Medicine, Eulji University College of Medicine, Seoul, Korea
– sequence: 3
  givenname: Hee Jung
  surname: Ahn
  fullname: Ahn, Hee Jung
  organization: Diabetes Center, Eulji Hospital, Seoul, Korea
– sequence: 4
  givenname: Hee Geum
  surname: Seok
  fullname: Seok, Hee Geum
  organization: Diabetes Center, Eulji Hospital, Seoul, Korea
– sequence: 5
  givenname: Jae Hyuk
  surname: Lee
  fullname: Lee, Jae Hyuk
  organization: Diabetes Center, Eulji Hospital, Seoul, Korea
– sequence: 6
  givenname: Gang Seo
  surname: Park
  fullname: Park, Gang Seo
  organization: Department of Internal Medicine, Eulji University College of Medicine, Seoul, Korea
– sequence: 7
  givenname: Kyung Ah
  surname: Han
  fullname: Han, Kyung Ah
  organization: Department of Internal Medicine, Eulji University College of Medicine, Seoul, Korea
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Copyright 2011. This work is licensed under http://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Copyright © 2011 Korean Diabetes Association 2011
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Issue 4
Keywords Endothelial function
Diabetes mellitus, type 2
Resistance training
Aerobic exercise
Language English
License http://creativecommons.org/licenses/by-nc/3.0
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content type line 14
content type line 23
Hwi Ryun Kwon and Kyung Wan Min contributed equally to this study as first authors.
G704-SER000002700.2011.35.4.003
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Snippet There is controversy over whether aerobic or resistance exercise is more effective for improving endothelial function in type 2 diabetes mellitus (T2DM). This...
Background There is controversy over whether aerobic or resistance exercise is more effective for improving endothelial function in type 2 diabetes mellitus...
BackgroundThere is controversy over whether aerobic or resistance exercise is more effective for improving endothelial function in type 2 diabetes mellitus...
Background: There is controversy over whether aerobic or resistance exercise is more effective for improving endothelial function in type 2 diabetes mellitus...
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StartPage 364
SubjectTerms Accelerometers
Aerobic exercise
Aerobics
Antihypertensives
Bioavailability
Blood pressure
Cardiovascular disease
Cholesterol
Diabetes
Diabetes mellitus, type 2
Drug dosages
Endothelial function
Energy intake
Exercise
Glucose
Heart failure
Hemoglobin
Nitric oxide
Original
Performance evaluation
Physical fitness
Resistance training
Smooth muscle
Strength training
Womens health
내과학
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Title Effects of Aerobic Exercise vs. Resistance Training on Endothelial Function in Women with Type 2 Diabetes Mellitus
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