Fluid-dynamics modelling of the human left ventricle with dynamic mesh for normal and myocardial infarction: Preliminary study

• Published in: Computers in biology and medicine Vol. 42; no. 8; pp. 863 - 870
• Main Authors: Khalafvand, S.S., Ng, E.Y.K., Zhong, L., Hung, T.K.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 01.08.2012
• Subjects: blood flow; Case-Control Studies; CFD; Diastole - physiology; Dynamic mesh; fluid mechanics; Heart - physiology; Heart Ventricles; Hemodynamics - physiology; Humans; Internal Medicine; Left ventricle; Magnetic Resonance Imaging, Cine; Models, Cardiovascular; MRI; myocardial infarction; Myocardial Infarction - physiopathology; Other; patients; Pressure difference; Systole - physiology; Ventricular Function; Vortices; CFD; Pressure difference; MRI; Vortices; Left ventricle; Dynamic mesh
• ISSN: 0010-4825; 1879-0534; 1879-0534
• DOI: 10.1016/j.compbiomed.2012.06.010

Pulsating blood flow patterns in the left ventricular (LV) were computed for three normal subjects and three patients after myocardial infarction (MI). Cardiac magnetic resonance (MR) images were obtained, segmented and transformed into 25 frames of LV for a computational fluid dynamics (CFD) study. Multi-block structure meshes were generated for 25 frames and 75 intermediate grids. The complete LV cycle was modelled by using ANSYS-CFX 12. The flow patterns and pressure drops in the LV chamber of this study provided some useful information on intra-LV flow patterns with heart diseases.