Successful epilepsy surgery in a patient with neurosarcoidosis

• Published in: Epilepsia (Copenhagen) Vol. 51; no. 6; pp. 1101 - 1103
• Main Authors: Malmgren, Kristina, Lycke, Jan, Engman, Elisabeth, Hedström, Anders, Jönsson, Lars, Rydenhag, Bertil, Nordborg, Claes
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.06.2010; Wiley-Blackwell
• Subjects: Adult; Anticonvulsants. Antiepileptics. Antiparkinson agents; Biological and medical sciences; Epilepsy - complications; Epilepsy - diagnosis; Epilepsy - surgery; Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy; Humans; Male; Medical sciences; Nervous system (semeiology, syndromes); Neurologi; Neurology; Neuropharmacology; Neurosarcoidosis; Pharmacology. Drug treatments; Sarcoidosis; Sarcoidosis - complications; Sarcoidosis - diagnosis; Sarcoidosis - surgery; Seizure outcome; Temporal Lobe - pathology; Temporal Lobe - surgery; Temporal lobe epilepsy; Treatment Outcome; Human; Nervous system diseases; Seizure outcome; Prognosis; Sarcoidosis; Complex partial epilepsy; Epilepsy surgery; Neurosarcoidosis; Cerebral disorder; Convulsion; Surgery; Systemic disease; Central nervous system disease; Temporal lobe epilepsy; Neurological disorder
• ISSN: 0013-9580; 1528-1167; 1528-1167
• DOI: 10.1111/j.1528-1167.2010.02580.x

Summary This case concerns a patient with generalized neurosarcoidosis and pharmacoresistant focal epilepsy. Although immunosuppressive therapy resulted in remission of the neurosarcoidosis, seizures continued and were shown to originate from the right temporal lobe (TL). The patient underwent a right anterior temporal lobe resection (TLR) and obtained >90% reduction of seizure frequency.