Enhancing percutaneous coronary intervention with heuristic path planning and deep-learning-based vascular segmentation

• Published in: Computers in biology and medicine Vol. 166; p. 107540
• Main Authors: Yao, Tianliang, Wang, Chengjia, Wang, Xinyi, Li, Xiang, Jiang, Zhaolei, Qi, Peng
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 01.11.2023; Elsevier Limited
• Subjects: Algorithms; Angioplasty; Cardiology; Coronary Vessels - diagnostic imaging; Coronary Vessels - surgery; Decision making; Deep Learning; Female; Hemodynamics; Heuristic; Heuristics; Humans; Image segmentation; Internal Medicine; Male; Medical imaging; Middle Aged; Other; Path planning; Percutaneous coronary intervention; Percutaneous Coronary Intervention - methods; Problem solving; Real time; Segmentation; Surgery assistance system; Vascular diseases; Vessel segmentation; Deep learning; Vessel segmentation; Percutaneous coronary intervention; Path planning; Surgery assistance system
• ISSN: 0010-4825; 1879-0534; 1879-0534
• DOI: 10.1016/j.compbiomed.2023.107540

Percutaneous coronary intervention (PCI) is a minimally invasive technique for treating vascular diseases. PCI requires precise and real-time visualization and guidance to ensure surgical safety and efficiency. Existing mainstream guiding methods rely on hemodynamic parameters. However, these methods are less intuitive than images and pose some challenges to the decision-making of cardiologists. This paper proposes a novel PCI guiding assistance system by combining a novel vascular segmentation network and a heuristic intervention path planning algorithm, providing cardiologists with clear and visualized information. A dataset of 1077 DSA images from 288 patients is also collected in clinical practice. A Likert Scale is also designed to evaluate system performance in user experiments. Results of user experiments demonstrate that the system can generate satisfactory and reasonable paths for PCI. Our proposed method outperformed the state-of-the-art baselines based on three metrics (Jaccard: 0.4091, F1: 0.5626, Accuracy: 0.9583). The proposed system can effectively assist cardiologists in PCI by providing a clear segmentation of vascular structures and optimal real-time intervention paths, thus demonstrating great potential for robotic PCI autonomy. •A novel system integrates deep learning and path planning to enhance PCI precision.•A SOTA vessel segmentation model and customized planning algorithm are adopted.•The system’s feasibility and remarkable performance have been demonstrated.•The system unlocks new possibilities in PCI and patient care for its accuracy.