Recurring Episodes of Bell’s Mania After Cerebrovascular Accident

• Published in: Psychosomatics (Washington, D.C.) Vol. 50; no. 3; pp. 285 - 288
• Main Authors: Bobo, William V., Murphy, Michael J., Heckers, Stephan H.
• Format: Journal Article
• Language: English
• Published: Arlington, VA Elsevier Inc 01.05.2009; American Psychiatric Publishing; Elsevier Limited
• Subjects: Adult and adolescent clinical studies; Anti-Anxiety Agents - therapeutic use; Biological and medical sciences; Bipolar Disorder - diagnosis; Bipolar Disorder - drug therapy; Bipolar Disorder - etiology; Bipolar Disorder - psychology; Brain Stem Infarctions - complications; Brain Stem Infarctions - psychology; Catatonia - diagnosis; Catatonia - drug therapy; Catatonia - etiology; Catatonia - psychology; Cerebellum - blood supply; Delirium - diagnosis; Delirium - drug therapy; Delirium - etiology; Delirium - psychology; Diagnosis, Differential; Dose-Response Relationship, Drug; Female; Humans; Internal Medicine; Lorazepam - therapeutic use; Mania; Medical sciences; Middle Aged; Mood disorders; Neurology; Neuropharmacology; Organic mental disorders. Neuropsychology; Pharmacology. Drug treatments; Pons - blood supply; Psychiatry; Psycholeptics: tranquillizer, neuroleptic; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychopharmacology; Recurrence; Vascular diseases and vascular malformations of the nervous system; Human; Mood disorder; Delirium; Nervous system diseases; Stroke; Psychotropic; Treatment efficiency; Pharmacotherapy; Cardiovascular disease; Recurrent; Cerebral disorder; Organic mental disorder; Vascular disease; Case study; Concomitant disease; Treatment; Tranquillizer; Central nervous system disease; Mania; Benzodiazepine derivatives; Adult; Lorazepam; Woman; Cerebrovascular disease
• ISSN: 0033-3182; 1545-7206; 1545-7206
• DOI: 10.1176/appi.psy.50.3.285

Bell’s mania (mania with delirium) is an acute neurobehavioral syndrome of unknown etiology that is characterized by the rapid onset of grandiosity, psychomotor excitement, emotional lability, psychosis, and sleep disruption consistent with mania, coupled with alterations in sensorium, and disorientation characteristic of delirium. Catatonia is a common feature of the syndrome. The authors describe a case of recurrent delirium/mania with prominent catatonic features after a cerebellar and pontine stroke, and subsequent successful treatment with lorazepam. Symptoms quickly resolved after antipsychotics were discontinued, with continuation of valproate and lorazapam treatment. Failure to recognize this patient’s syndrome as a form of catatonia could have had severe, even life-threatening, consequences. The use of neuroleptic medications in cases of delirium/mania with catatonic signs may result in marked clinical deterioration, whereas high-dose lorazepam can ameliorate catatonic signs.