Monitoring breath markers under controlled conditions

Breath analysis has the potential to detect and monitor diseases as well as to reduce the corresponding medical costs while improving the quality of a patient's life. Herein, a portable prototype, consisting of a commercial breath sampler modified to work as a platform for solid-state gas senso...

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Bibliographic Details
Published inJournal of breath research Vol. 9; no. 4; p. 47101
Main Authors Righettoni, Marco, Ragnoni, Alessandro, Güntner, Andreas T, Loccioni, Claudio, Pratsinis, Sotiris E, Risby, Terence H
Format Journal Article
LanguageEnglish
Published England IOP Publishing 15.10.2015
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ISSN1752-7155
1752-7163
1752-7163
DOI10.1088/1752-7155/9/4/047101

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Summary:Breath analysis has the potential to detect and monitor diseases as well as to reduce the corresponding medical costs while improving the quality of a patient's life. Herein, a portable prototype, consisting of a commercial breath sampler modified to work as a platform for solid-state gas sensors was developed. The sensor is placed close to the mouth (<10 cm) and minimizes the mouth-to-sensor path to avoid contamination and dilution of the target breath marker. Additionally with an appropriate cooling concept, even high sensor operating temperatures (e.g. 350 °C) could be used. Controlled sampling is crucial for accurate repeatable analysis of the human breath and these concerns have been addressed by this novel prototype. The device helps a subject control their exhaled flow rate which increases reproducibility of intra-subject breath samples. The operation of this flame-made selective chemo-resistive gas sensor is demonstrated by the detection of breath acetone.
Bibliography:JBR-100223.R1
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ISSN:1752-7155
1752-7163
1752-7163
DOI:10.1088/1752-7155/9/4/047101