Risk factors for premature coronary artery disease and determinants of adverse outcomes after revascularization in patients ≤40 years old

• Published in: The American journal of cardiology Vol. 92; no. 12; pp. 1465 - 1467
• Main Authors: Mukherjee, Debabrata, Hsu, Amy, Moliterno, David J, Lincoff, A.Michael, Goormastic, Marlene, Topol, Eric J
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 15.12.2003; Elsevier
• Subjects: Adult; Age Factors; Angioplasty, Balloon; Biological and medical sciences; Cardiology. Vascular system; Coronary Artery Bypass; Coronary Artery Disease - etiology; Coronary Artery Disease - mortality; Coronary Artery Disease - therapy; Coronary heart disease; Female; Heart; Humans; Male; Medical sciences; Middle Aged; Myocardial Infarction - complications; Myocardial Revascularization; Risk Factors; Sex Factors; Smoking - adverse effects; Smoking - epidemiology; Stents; Human; Prognosis; Coronary artery; Tobacco smoking; Instrumentation therapy; Cardiovascular disease; Instrumental dilatation; Coronary heart disease; Toxicology; Treatment; Aortocoronary; Bypass; Follow up study; Surgery; Risk factor; Age
• ISSN: 0002-9149; 1879-1913
• DOI: 10.1016/j.amjcard.2003.08.062

Smoking is an important and modifiable risk factor associated with premature atherosclerosis and the need for coronary revascularization in young adult patients ≤40 years old. Although intermediate and long-term survival is better in young adult patients after percutaneous coronary intervention, co-morbidities such as low ejection fraction, previous myocardial infarction, and previous bypass surgery are important adverse prognostic determinants.