Childhood Cardiovascular Risk Factors and Adult Cardiovascular Events

In this study, childhood cardiovascular risk factors including BMI, systolic blood pressure, lipid levels, and smoking were correlated with cardiovascular events in adulthood after a mean follow-up of 35 years. Childhood risk factors and the change in risk score between childhood and adulthood were...

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Bibliographic Details
Published inThe New England journal of medicine Vol. 386; no. 20; pp. 1877 - 1888
Main Authors Jacobs, David R., Woo, Jessica G., Sinaiko, Alan R., Daniels, Stephen R., Ikonen, Johanna, Juonala, Markus, Kartiosuo, Noora, Lehtimäki, Terho, Magnussen, Costan G., Viikari, Jorma S.A., Zhang, Nanhua, Bazzano, Lydia A., Burns, Trudy L., Prineas, Ronald J., Steinberger, Julia, Urbina, Elaine M., Venn, Alison J., Raitakari, Olli T., Dwyer, Terence
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 19.05.2022
Subjects
Adolescent
Adult
Adults
Age
Blood pressure
Cardiology
Cardiovascular disease
Cardiovascular diseases
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - etiology
Child
Child development
Child, Preschool
Childhood
Children
Cholesterol
Clinical Medicine
Clinical Medicine General
Consent
Consortia
Female
Heart Disease Risk Factors
Humans
Hypotheses
Male
Medical records
Pediatrics
Pediatrics General
Prevention
Prospective Studies
Public Health
Public Health General
Risk Factors
Smoking
Statistical analysis
Triglycerides
Young Adult
United States > US
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ISSN0028-4793
1533-4406
1533-4406
DOI10.1056/NEJMoa2109191

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Summary:In this study, childhood cardiovascular risk factors including BMI, systolic blood pressure, lipid levels, and smoking were correlated with cardiovascular events in adulthood after a mean follow-up of 35 years. Childhood risk factors and the change in risk score between childhood and adulthood were associated with midlife cardiovascular events.
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Drs. Jacobs, Woo, and Sinaiko and Drs. Bazzano, Burns, Prineas, Steinberger, Urbina, Venn, Raitakari, and Dwyer contributed equally to this article.
The authors’ full names, academic degrees, and affiliations are listed in the Appendix.
ISSN:0028-4793
1533-4406
1533-4406
DOI:10.1056/NEJMoa2109191