A clinical study of microcirculatory disturbance in Chinese patients with sudden deafness

Conclusion. Cochlear microcirculation disturbance is closely associated with sudden deafness. Objectives. To investigate the relationship between cochlear microcirculation and sudden deafness. Subjects and methods. Clinical laboratory parameters (clinical chemistry, hemorheology, hematology, and hem...

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Bibliographic Details
Published inActa oto-laryngologica Vol. 128; no. 11; pp. 1168 - 1172
Main Authors Lu, Yuan-Yuan, Jin, Zhe, Tong, Bu-Sheng, Yang, Jian-Ming, Liu, Ye-Hai, Duan, Maoli
Format Journal Article
LanguageEnglish
Published Stockholm Informa UK Ltd 01.01.2008
Taylor & Francis
Taylor and Francis
Subjects
Adult
Aged
Biological and medical sciences
Blood Viscosity
Cholesterol - blood
Female
Hearing Loss, Sensorineural - blood
Hearing Loss, Sudden - blood
Hemorheology
Hemostasis
Humans
Lipoproteins - blood
Male
Medical sciences
Microcirculation
microcirculation disturbance
Middle Aged
Otorhinolaryngology. Stomatology
serum lipid
Sudden deafness
Triglycerides - blood
Young Adult
Asia
China
Human
Microcirculation
Symptomatology
Sudden hearing loss
serum lipid
Lipids
Serum
hemorheology
ENT
Sudden deafness
microcirculation disturbance
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ISSN0001-6489
1651-2251
1651-2251
DOI10.1080/00016480801901626

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Summary:Conclusion. Cochlear microcirculation disturbance is closely associated with sudden deafness. Objectives. To investigate the relationship between cochlear microcirculation and sudden deafness. Subjects and methods. Clinical laboratory parameters (clinical chemistry, hemorheology, hematology, and hemostasis determinations) were studied in 86 patients with sudden deafness and 30 healthy control subjects. Results. The levels of total cholesterol (TCH), triglyceride (TG), and lipoprotein A were significantly higher in patients with sudden deafness than in control subjects. Plasma viscosity, ratio viscosity of whole blood, reduced viscosity of whole blood, high and low shear relative viscosity of whole blood, index of red blood cells transmutation, and fibrinogen level in the plasma of patients with sudden sensorineural hearing loss (SSNHL) were also significantly elevated in comparison with those in control subjects. White-collar workers with psychological and behavioral abnormalities tend to suffer from sudden deafness.
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ISSN:0001-6489
1651-2251
1651-2251
DOI:10.1080/00016480801901626