TEG®- or ROTEM®-based individualized goal-directed coagulation algorithms: don’t wait - act now

In trauma patients, TEG ® and ROTEM ® allow prediction of massive transfusion requirement and mortality, and creation of goal-directed, individualized coagulation algorithms that may improve patient outcome. This outcome benefit has been shown for cardiac surgery in prospective randomized trials. Fo...

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Bibliographic Details
Published in	Critical care (London, England) Vol. 18; no. 6; p. 637
Main Author	Spahn, Donat R
Format	Journal Article
Language	English
Published	London BioMed Central 24.11.2014 BioMed Central Ltd
Subjects	Blood Coagulation Disorders - diagnosis Blood Coagulation Disorders - therapy Blood Transfusion Commentary Critical Care Medicine Emergency Medicine Health aspects Humans Intensive Medical research Medicine Medicine & Public Health Medicine, Experimental Methods Patient compliance Thrombelastography - methods Wounds and Injuries - complications Trauma Patient Improve Patient Outcome Tranexamic Acid Massive Transfusion Blood Product Transfusion
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ISSN	1364-8535 1466-609X 1364-8535 1466-609X
DOI	10.1186/s13054-014-0637-3

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Summary:	In trauma patients, TEG ® and ROTEM ® allow prediction of massive transfusion requirement and mortality, and creation of goal-directed, individualized coagulation algorithms that may improve patient outcome. This outcome benefit has been shown for cardiac surgery in prospective randomized trials. For trauma, only non-randomized studies have been performed. Nevertheless, TEG ® and ROTEM ® are highly promising monitoring techniques to guide coagulation management in all types of major bleeding, including trauma.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Commentary-3 content type line 23
ISSN:	1364-8535 1466-609X 1364-8535 1466-609X
DOI:	10.1186/s13054-014-0637-3