Roles of the Cell Surface Architecture of Bacteroides and Bifidobacterium in the Gut Colonization

There are numerous bacteria reside within the mammalian gastrointestinal tract. Among the intestinal bacteria, Akkermansia , Bacteroides , Bifidobacterium , and Ruminococcus closely interact with the intestinal mucus layer and are, therefore, known as mucosal bacteria. Mucosal bacteria use host or d...

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Published inFrontiers in microbiology Vol. 12; p. 754819
Main Authors Nishiyama, Keita, Yokoi, Tatsunari, Sugiyama, Makoto, Osawa, Ro, Mukai, Takao, Okada, Nobuhiko
Format Journal Article
LanguageEnglish
Published Frontiers Media S.A 14.10.2021
Subjects
adhesion
Bacteroides
Bifidobacterium
cell surface protein
Microbiology
mucin
mucosal bacteria
Online AccessGet full text
ISSN1664-302X
1664-302X
DOI10.3389/fmicb.2021.754819

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Abstract There are numerous bacteria reside within the mammalian gastrointestinal tract. Among the intestinal bacteria, Akkermansia , Bacteroides , Bifidobacterium , and Ruminococcus closely interact with the intestinal mucus layer and are, therefore, known as mucosal bacteria. Mucosal bacteria use host or dietary glycans for colonization via adhesion, allowing access to the carbon source that the host’s nutrients provide. Cell wall or membrane proteins, polysaccharides, and extracellular vesicles facilitate these mucosal bacteria-host interactions. Recent studies revealed that the physiological properties of Bacteroides and Bifidobacterium significantly change in the presence of co-existing symbiotic bacteria or markedly differ with the spatial distribution in the mucosal niche. These recently discovered strategic colonization processes are important for understanding the survival of bacteria in the gut. In this review, first, we introduce the experimental models used to study host-bacteria interactions, and then, we highlight the latest discoveries on the colonization properties of mucosal bacteria, focusing on the roles of the cell surface architecture regarding Bacteroides and Bifidobacterium .
AbstractList There are numerous bacteria reside within the mammalian gastrointestinal tract. Among the intestinal bacteria, Akkermansia, Bacteroides, Bifidobacterium, and Ruminococcus closely interact with the intestinal mucus layer and are, therefore, known as mucosal bacteria. Mucosal bacteria use host or dietary glycans for colonization via adhesion, allowing access to the carbon source that the host’s nutrients provide. Cell wall or membrane proteins, polysaccharides, and extracellular vesicles facilitate these mucosal bacteria-host interactions. Recent studies revealed that the physiological properties of Bacteroides and Bifidobacterium significantly change in the presence of co-existing symbiotic bacteria or markedly differ with the spatial distribution in the mucosal niche. These recently discovered strategic colonization processes are important for understanding the survival of bacteria in the gut. In this review, first, we introduce the experimental models used to study host-bacteria interactions, and then, we highlight the latest discoveries on the colonization properties of mucosal bacteria, focusing on the roles of the cell surface architecture regarding Bacteroides and Bifidobacterium.
There are numerous bacteria reside within the mammalian gastrointestinal tract. Among the intestinal bacteria, Akkermansia, Bacteroides, Bifidobacterium, and Ruminococcus closely interact with the intestinal mucus layer and are, therefore, known as mucosal bacteria. Mucosal bacteria use host or dietary glycans for colonization via adhesion, allowing access to the carbon source that the host's nutrients provide. Cell wall or membrane proteins, polysaccharides, and extracellular vesicles facilitate these mucosal bacteria-host interactions. Recent studies revealed that the physiological properties of Bacteroides and Bifidobacterium significantly change in the presence of co-existing symbiotic bacteria or markedly differ with the spatial distribution in the mucosal niche. These recently discovered strategic colonization processes are important for understanding the survival of bacteria in the gut. In this review, first, we introduce the experimental models used to study host-bacteria interactions, and then, we highlight the latest discoveries on the colonization properties of mucosal bacteria, focusing on the roles of the cell surface architecture regarding Bacteroides and Bifidobacterium.There are numerous bacteria reside within the mammalian gastrointestinal tract. Among the intestinal bacteria, Akkermansia, Bacteroides, Bifidobacterium, and Ruminococcus closely interact with the intestinal mucus layer and are, therefore, known as mucosal bacteria. Mucosal bacteria use host or dietary glycans for colonization via adhesion, allowing access to the carbon source that the host's nutrients provide. Cell wall or membrane proteins, polysaccharides, and extracellular vesicles facilitate these mucosal bacteria-host interactions. Recent studies revealed that the physiological properties of Bacteroides and Bifidobacterium significantly change in the presence of co-existing symbiotic bacteria or markedly differ with the spatial distribution in the mucosal niche. These recently discovered strategic colonization processes are important for understanding the survival of bacteria in the gut. In this review, first, we introduce the experimental models used to study host-bacteria interactions, and then, we highlight the latest discoveries on the colonization properties of mucosal bacteria, focusing on the roles of the cell surface architecture regarding Bacteroides and Bifidobacterium.
There are numerous bacteria reside within the mammalian gastrointestinal tract. Among the intestinal bacteria, Akkermansia , Bacteroides , Bifidobacterium , and Ruminococcus closely interact with the intestinal mucus layer and are, therefore, known as mucosal bacteria. Mucosal bacteria use host or dietary glycans for colonization via adhesion, allowing access to the carbon source that the host’s nutrients provide. Cell wall or membrane proteins, polysaccharides, and extracellular vesicles facilitate these mucosal bacteria-host interactions. Recent studies revealed that the physiological properties of Bacteroides and Bifidobacterium significantly change in the presence of co-existing symbiotic bacteria or markedly differ with the spatial distribution in the mucosal niche. These recently discovered strategic colonization processes are important for understanding the survival of bacteria in the gut. In this review, first, we introduce the experimental models used to study host-bacteria interactions, and then, we highlight the latest discoveries on the colonization properties of mucosal bacteria, focusing on the roles of the cell surface architecture regarding Bacteroides and Bifidobacterium .
Author Yokoi, Tatsunari
Sugiyama, Makoto
Nishiyama, Keita
Okada, Nobuhiko
Osawa, Ro
Mukai, Takao
AuthorAffiliation 3 Laboratory of Veterinary Anatomy, School of Veterinary Medicine, Kitasato University , Towada , Japan
5 Department of Animal Science, School of Veterinary Medicine, Kitasato University , Towada , Japan
4 Research Center for Food Safety and Security, Kobe University , Kobe , Japan
2 Department of Microbiology, School of Pharmacy, Kitasato University , Tokyo , Japan
1 Department of Microbiology and Immunology, Keio University School of Medicine , Tokyo , Japan
AuthorAffiliation_xml – name: 2 Department of Microbiology, School of Pharmacy, Kitasato University , Tokyo , Japan
– name: 5 Department of Animal Science, School of Veterinary Medicine, Kitasato University , Towada , Japan
– name: 3 Laboratory of Veterinary Anatomy, School of Veterinary Medicine, Kitasato University , Towada , Japan
– name: 1 Department of Microbiology and Immunology, Keio University School of Medicine , Tokyo , Japan
– name: 4 Research Center for Food Safety and Security, Kobe University , Kobe , Japan
Author_xml – sequence: 1
  givenname: Keita
  surname: Nishiyama
  fullname: Nishiyama, Keita
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  surname: Osawa
  fullname: Osawa, Ro
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  givenname: Takao
  surname: Mukai
  fullname: Mukai, Takao
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  givenname: Nobuhiko
  surname: Okada
  fullname: Okada, Nobuhiko
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Edited by: Francesca Bottacini, Munster Technological University, Ireland
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Snippet There are numerous bacteria reside within the mammalian gastrointestinal tract. Among the intestinal bacteria, Akkermansia , Bacteroides , Bifidobacterium ,...
There are numerous bacteria reside within the mammalian gastrointestinal tract. Among the intestinal bacteria, Akkermansia, Bacteroides, Bifidobacterium, and...
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SubjectTerms adhesion
Bacteroides
Bifidobacterium
cell surface protein
Microbiology
mucin
mucosal bacteria
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Title Roles of the Cell Surface Architecture of Bacteroides and Bifidobacterium in the Gut Colonization
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