Clinical and prognostic aspects of laryngeal clear cell carcinoma

• Published in: Journal of laryngology and otology Vol. 119; no. 12; pp. 991 - 994
• Main Authors: Testa, Domenico, Galli, Vieri, de Rosa, Gaetano, Iovine, Renata, Staibano, Stefania, Somma, Pasquale, Mignogna, Chiara, Iengo, Maurizio
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 01.12.2005
• Subjects: (RF) Otorhinolaryngology; Adenocarcinoma, Clear Cell - mortality; Adenocarcinoma, Clear Cell - pathology; Adenocarcinoma, Clear Cell - therapy; Biological and medical sciences; Clear Cell Carcinoma; Humans; Laryngeal Neoplasms - mortality; Laryngeal Neoplasms - pathology; Laryngeal Neoplasms - therapy; Laryngectomy; Larynx; Male; Medical sciences; Middle Aged; Neoplasm Recurrence, Local - mortality; Neoplasm Recurrence, Local - therapy; Otorhinolaryngology. Stomatology; Prognosis; Surgical Procedures; Surgical Procedures; Larynx; Clear Cell Carcinoma; Case study; Human; Symptomatology; Clear cell carcinoma; Prognosis; Treatment; Surgery; ENT; Malignant tumor
• ISSN: 0022-2151; 1748-5460
• DOI: 10.1258/002221505775010715

Clear cell carcinoma (CCC) of the larynx is a rare pathological finding; only eight cases are described in the literature. It occurs in older adults and shows a predilection for men. We report the ninth observation of laryngeal CCC in the literature. We reviewed the literature and correlated the prognosis of the tumour according to its site of onset and treatment. The literature review showed that this neoplasm is highly aggressive, with a high recurrence rate and short mean survival time; the treatment of choice is surgery, and chemo- or radiotherapy are used mainly for the treatment of recurrences.