The measurement of patient attitudes regarding prenatal and preconception genetic carrier screening and translational behavioral medicine: an integrative review

• Published in: Translational behavioral medicine Vol. 7; no. 2; pp. 364 - 370
• Main Authors: Shiroff, Jennifer J., Gregoski, Mathew J.
• Format: Journal Article
• Language: English
• Published: New York Oxford University Press 01.06.2017; Springer US
• Subjects: Attitudes; Behavior; Cross Cultural Psychology; Cystic fibrosis; Disease; Family medical history; Family Medicine; General Practice; Genetic Carrier Screening; Genetic disorders; Health Knowledge, Attitudes, Practice; Health Promotion and Disease Prevention; Health Psychology; Humans; Medical screening; Medicine; Medicine & Public Health; Mutation; Nursing; Original Research; Patients; Pregnancy; Prenatal Diagnosis; Public Health; Surveys and Questionnaires; Validity; Pregnancy; Integrative review; Conception; Patient; Genetic testing; Attitude
• ISSN: 1869-6716; 1613-9860
• DOI: 10.1007/s13142-015-0346-8

Measurement of recessive carrier screening attitudes related to conception and pregnancy is necessary to determine current acceptance, and whether behavioral intervention strategies are needed in clinical practice. To evaluate quantitative survey instruments to measure patient attitudes regarding genetic carrier testing prior to conception and pregnancy databases examining patient attitudes regarding genetic screening prior to conception and pregnancy from 2003–2013 were searched yielding 344 articles; eight studies with eight instruments met criteria for inclusion. Data abstraction on theoretical framework, subjects, instrument description, scoring, method of measurement, reliability, validity, feasibility, level of evidence, and outcomes was completed. Reliability information was provided in five studies with an internal consistency of Cronbach's α >0.70. Information pertaining to validity was presented in three studies and included construct validity via factor analysis. Despite limited psychometric information, these questionnaires are self-administered and can be briefly completed, making them a feasible method of evaluation.