Elucidating the molecular circuitry of autoimmunity

Novel single-cell profiling technologies have delineated the cellular and molecular landscapes that dominate the joints in rheumatoid arthritis and the skin and kidneys in systemic lupus erythematosus, shedding light on potential pathogenic mechanisms.

Saved in:

Bibliographic Details
Published in	Nature immunology Vol. 20; no. 7; pp. 777 - 778
Main Authors	Varadarajan, Navin, Mohan, Chandra
Format	Journal Article
Language	English
Published	New York Nature Publishing Group US 01.07.2019 Nature Publishing Group
Subjects	631/1647/2017 631/250/249/1313/1613/1614 631/250/249/1313/498 631/250/256/2515 631/250/38 Animals Autoimmune diseases Autoimmune Diseases - diagnosis Autoimmune Diseases - etiology Autoimmune Diseases - metabolism Autoimmunity Autoimmunity - genetics B cells Biomarkers Biomedical and Life Sciences Biomedicine Correlation analysis Cytokines Disease Flow cytometry Gene Expression Profiling Humans Hypotheses Immunology Infectious Diseases Inflammation Joint diseases Kidneys Ligands Lupus Lymphocytes News & Views news-and-views Protein expression Proteins Rheumatoid arthritis Rheumatoid factor Single-Cell Analysis - methods Skin Systemic lupus erythematosus Transcriptome Urine
Online Access	Get full text
ISSN	1529-2908 1529-2916 1529-2916
DOI	10.1038/s41590-019-0436-8

Cover

More Information
Summary:	Novel single-cell profiling technologies have delineated the cellular and molecular landscapes that dominate the joints in rheumatoid arthritis and the skin and kidneys in systemic lupus erythematosus, shedding light on potential pathogenic mechanisms.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 ObjectType-Correspondence-1
ISSN:	1529-2908 1529-2916 1529-2916
DOI:	10.1038/s41590-019-0436-8