Detection and recurrence rate of transurethral resection of bladder tumors by narrow-band imaging: Prospective, randomized comparison with white light cystoscopy

• Published in: Investigative and clinical urology Vol. 59; no. 2; pp. 98 - 105
• Main Authors: Kim, Seung Bin, Yoon, Sung Goo, Tae, Jonghyun, Kim, Jae Yoon, Shim, Ji Sung, Kang, Sung Gu, Cheon, Jun, Lee, Jeong Gu, Kim, Je Jong, Kang, Seok Ho
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Urological Association 01.03.2018; Korean Urological Association; 대한비뇨의학회
• Subjects: Aged; Cystectomy - adverse effects; Cystectomy - methods; Cystoscopy - instrumentation; Cystoscopy - methods; Female; Humans; Lighting - methods; Male; Middle Aged; Narrow band imaging; Narrow Band Imaging - methods; Neoplasm Recurrence, Local - pathology; Neoplasm Recurrence, Local - prevention & control; Neoplasm Staging; Original; Outcome Assessment (Health Care); Urinary bladder neoplasms; Urinary Bladder Neoplasms - diagnosis; Urinary Bladder Neoplasms - pathology; Urinary Bladder Neoplasms - surgery; 비뇨기과학; Urinary bladder neoplasms; Narrow band imaging
• ISSN: 2466-0493; 2466-054X; 2466-054X
• DOI: 10.4111/icu.2018.59.2.98

The purpose of this study was to evaluate the efficacy of narrow-band imaging (NBI) as a diagnostic tool for detecting bladder tumors during cystoscopy compared with white light cystoscopy (WLC). From December 2013 to June 2017, a randomized prospective study was conducted on 198 patients underwent transurethral resection of bladder tumor by a single surgeon. The patients were divided into two groups according to diagnostic method. In Group I, WLC only was performed. In Group II, NBI was additionally performed after WLC. We analyzed the rate of detection of bladder tumors as a primary endpoint. In addition, we evaluated rates of recurrence in each group. There were no significant differences between the two groups in characteristics except hypertension. In the analysis of rates of detection, the probability of diagnosing cancer was 80.9% (114/141) in the WLC group, and the probability of diagnosing cancer using WLC in the NBI group was 85.5% (159/186). After switching from WLC to NBI for second-look cystoscopy in the NBI group, NBI was shown to detect additional tumors with a detection rate of 35.1% (13/37) from the perspective of the patients and 42.2% (27/64) from the perspective of the tumors. The 1-year recurrence-free rate was 72.2% in the WLC group and 85.2% in the NBI group (p=0.3). NBI had benefits for detecting tumors overlooked by WLC. Although the difference in the 1-year recurrence-free rate was not statistically significant, our results showed a trend for higher recurrence in the NBI group.