Bone scintigraphy based on deep learning model and modified growth optimizer

• Published in: Scientific reports Vol. 14; no. 1; pp. 25627 - 17
• Main Authors: Magdy, Omnia, Elaziz, Mohamed Abd, Dahou, Abdelghani, Ewees, Ahmed A., Elgarayhi, Ahmed, Sallah, Mohammed
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 27.10.2024; Nature Publishing Group; Nature Portfolio
• Subjects: 631/114; 631/114/1305; 631/114/1564; Algorithms; Arithmetic optimization algorithm (AOA); Bone and Bones - diagnostic imaging; Bone growth; Bone metastasis; Bone Neoplasms - diagnostic imaging; Bone Neoplasms - secondary; Bone scintigraphy; Deep Learning; Growth optimizer (GO); Humanities and Social Sciences; Humans; Image processing; Image Processing, Computer-Assisted - methods; Machine learning; Metastases; multidisciplinary; Nuclear medicine; Radionuclide Imaging - methods; Science; Science (multidisciplinary); Scintigraphy; Statistical analysis; Arithmetic optimization algorithm (AOA); Nuclear medicine; Bone metastasis; Growth optimizer (GO); Bone scintigraphy
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-024-73991-8

Bone scintigraphy is recognized as an efficient diagnostic method for whole-body screening for bone metastases. At the moment, whole-body bone scan image analysis is primarily dependent on manual reading by nuclear medicine doctors. However, manual analysis needs substantial experience and is both stressful and time-consuming. To address the aforementioned issues, this work proposed a machine-learning technique that uses phases to detect Bone scintigraphy. The first phase in the proposed model is the feature extraction and it was conducted based on integrating the Mobile Vision Transformer (MobileViT) model in our framework to capture highly complex representations from raw medical imagery using two primary components including ViT and lightweight CNN featuring a limited number of parameters. In addition, the second phase is named feature selection, and it is dependent on the Arithmetic Optimization Algorithm (AOA) being used to improve the Growth Optimizer (GO). We evaluate the performance of the proposed FS model, named GOAOA using a set of 18 UCI datasets. Additionally, the applicability of Bone scintigraphy for real-world application is evaluated using 2800 bone scan images (1400 normal and 1400 abnormal). The results and statistical analysis revealed that the proposed GOAOA algorithm as an FS technique outperforms the other FS algorithms employed in this study.