Reference values for ultrasonograpy of peripheral nerves

• Published in: Muscle & nerve Vol. 53; no. 4; pp. 538 - 544
• Main Authors: Qrimli, Mohammad, Ebadi, Hamid, Breiner, Ari, Siddiqui, Hafsah, Alabdali, Majed, Abraham, Alon, Lovblom, Leif E., Perkins, Bruce A., Bril, Vera
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.04.2016; Wiley Subscription Services, Inc
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; cross-sectional area; Female; Gender; Humans; Male; Middle Aged; Nervous system; Neural Conduction - physiology; neuropathy; peripheral nerve; Peripheral Nerves - diagnostic imaging; Peripheral Nerves - physiology; Reference Values; Ultrasonography, Interventional - methods; Ultrasonography, Interventional - standards; ultrasound; Young Adult; cross-sectional area; neuropathy; reference values; peripheral nerve; ultrasound
• ISSN: 0148-639X; 1097-4598
• DOI: 10.1002/mus.24888

ABSTRACT Introduction: High‐resolution ultrasonography (HRU) is a novel method that provides morphological information about peripheral nerves. We aimed to determine reference values for nerve cross‐sectional area (CSA) on HRU. Methods: One hundred healthy volunteers had HRU of median, radial, ulnar, fibular, tibial, sural, and superficial fibular nerves at defined sites. The CSA was measured and the effects of age, gender, and body mass index (BMI) were evaluated. Results: CSA values in healthy subjects are described. CSA is larger in lower limb motor nerves than in sensory nerves at similar sites, and the CSA tends to be symmetrical. The strongest effect on CSA was for age, although gender and BMI had some effects. Conclusions: This study provides normative values for HRU, and it suggests that further research with age‐ and gender‐specific distributions must be a key priority in the development of HRU for use as a diagnostic test for peripheral nerve diseases. Muscle Nerve 53: 538–544, 2016